Safety and Efficacy of Inpatient Diabetes Management with Non-insulin Agents: an Overview of International Practices.

IF 5.2 2区 医学 Q1 ENDOCRINOLOGY & METABOLISM
Rodolfo J Galindo, Ketan Dhatariya, Fernando Gomez-Peralta, Guillermo E Umpierrez
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引用次数: 7

Abstract

Purpose of review: The field of inpatient diabetes has advanced significantly over the last 20 years, leading to the development of personalized treatment approaches. However, outdated guidelines still recommend the use of basal-bolus insulin therapy as the preferred treatment approach, and against the use of non-insulin anti-hyperglycemic agents.

Recent findings: Several observational and prospective randomized controlled studies have demonstrated that oral anti-hyperglycemic agents are widely used in the hospital, including studies of DPP-4 agents and GLP-1 agonists. With advances in the field of inpatient diabetes management, a paradigm shift has occurred, from an approach of recommending "basal-bolus regimens" for all patients to a more precision medicine option for hospitalized non-critically ill patients with type 2 diabetes.

Abstract Image

非胰岛素药物治疗住院糖尿病患者的安全性和有效性:国际实践综述。
回顾目的:在过去的20年里,住院糖尿病领域取得了显著的进展,导致了个性化治疗方法的发展。然而,过时的指南仍然推荐使用基础胰岛素治疗作为首选治疗方法,反对使用非胰岛素降糖药。最近发现:一些观察性和前瞻性随机对照研究表明,口服降糖药物在医院被广泛使用,包括DPP-4药物和GLP-1激动剂的研究。随着住院糖尿病管理领域的进步,已经发生了范式转变,从推荐所有患者的“基础-大剂量方案”的方法到针对住院非危重2型糖尿病患者的更精确的药物选择。
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来源期刊
CiteScore
9.80
自引率
0.00%
发文量
52
审稿时长
6-12 weeks
期刊介绍: The goal of this journal is to publish cutting-edge reviews on subjects pertinent to all aspects of diabetes epidemiology, pathophysiology, and management. We aim to provide incisive, insightful, and balanced contributions from leading experts in each relevant domain that will be of immediate interest to a wide readership of clinicians, basic scientists, and translational investigators. We accomplish this aim by appointing major authorities to serve as Section Editors in key subject areas across the discipline. Section Editors select topics to be reviewed by leading experts who emphasize recent developments and highlight important papers published over the past year on their topics, in a crisp and readable format. We also provide commentaries from well-known figures in the field, and an Editorial Board of internationally diverse members suggests topics of special interest to their country/region and ensures that topics are current and include emerging research.
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