Gastroesophageal Reflux Characteristics in Supragastric Belching Patients With Positive Versus Negative pH Monitoring: An Evidence of Secondary Gastroesophageal Reflux Disease From Excessive Belching.

IF 3.3 3区 医学 Q2 CLINICAL NEUROLOGY
Suriya Keeratichananont, Tanisa Patcharatrakul, Sutep Gonlachanvit
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引用次数: 1

Abstract

Background/aims: A high prevalence of GERD has been reported in patients with supragastric belching. We aim to evaluate reflux characteristics and explore the temporal relationship between supragastric belches (SGBs) and reflux episodes in GERD patients with excessive belching.

Methods: Twenty-four hour esophageal pH-impedance monitoring was analyzed. Reflux episodes were classified into: refluxes preceded by SGBs, followed by SGBs, and lone refluxes. Reflux characteristics were compared between patients with pH-positive (pH+) and pH-negative(pH-).

Results: Forty-six patients (34 Female, age 47 ± 13 years) were included. Fifteen patients (32.6%) had pH+. Almost half (48.1 ± 21.0%) of refluxes were preceded by SGBs. The number of SGBs significantly correlated with the number of reflux episodes preceded by SGBs (r = 0.43, P < 0.05) and % time pH < 4 at the distal esophagus (r = 0.41, P < 0.05). Patients with pH+ had significantly more SGBs and reflux episodes preceded by SGBs/day than pH- patients (P < 0.05). The difference in the number of refluxes between pH+ and pH- patients was caused by reflux episodes preceded by SGBs, but not lone refluxes and refluxes followed by SGBs. The proportion of SGBs followed by reflux/total SGBs was similar between patients with pH+ and pH- (P > 0.05). Reflux episodes preceded by SGBs and followed by SGBs extended more proximal and had longer bolus and acid contact time than lone refluxes (P < 0.05).

Conclusions: In patients with GERD and SGB, the number of SGBs positively correlates with the number of reflux episodes preceded by SGBs. Identifying and managing SGB may be beneficial and more likely to improve GERD.

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Abstract Image

Abstract Image

胃上嗳气患者pH值监测阳性与阴性的胃食管反流特征:过度打嗝继发性胃食管反流病的证据
背景/目的:据报道胃上嗳气患者的胃反流发生率很高。我们的目的是评估反流特征,并探讨胃上嗳气(SGBs)与反流发作在胃食管反流患者中的时间关系。方法:对24 h食管ph -阻抗监测结果进行分析。反流发作分为:先发生sgb的反流、后发生sgb的反流和单独的反流。比较pH阳性(pH+)和pH阴性(pH-)患者的反流特征。结果:纳入46例患者,其中女性34例,年龄47±13岁。pH+ 15例(32.6%)。近一半(48.1±21.0%)的反流发生在sgb之前。食管远端胃液返流发生次数与食管远端胃液返流发生次数(r = 0.43, P < 0.05)和pH < 4时%相关(r = 0.41, P < 0.05)。与pH-患者相比,pH+患者的sbg发生率和反流发生率均显著高于pH-患者(P < 0.05)。pH+和pH-患者返流次数的差异是由返流发作前的sbg引起的,而不是单独的返流和回流后的sbg引起的。pH+和pH-患者胃液返流后sbg的比例/总sbg的比例相似(P > 0.05)。与单独的反流相比,sgb前后的反流发作更近端延伸,丸和酸接触时间更长(P < 0.05)。结论:在GERD和SGB患者中,SGB的数量与SGB之前的反流发作次数呈正相关。识别和管理SGB可能是有益的,更有可能改善胃食管反流。
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来源期刊
Journal of Neurogastroenterology and Motility
Journal of Neurogastroenterology and Motility GASTROENTEROLOGY & HEPATOLOGY-CLINICAL NEUROLOGY
CiteScore
6.30
自引率
8.80%
发文量
96
期刊介绍: Journal of Neurogastroenterology and Motility (J Neurogastroenterol Motil) is a joint official journal of the Korean Society of Neurogastroenterology and Motility, the Thai Neurogastroenterology and Motility Society, the Japanese Society of Neurogastroenterology and Motility, the Indian Motility and Functional Disease Association, the Chinese Society of Gastrointestinal Motility, the South East Asia Gastro-Neuro Motility Association, the Taiwan Neurogastroenterology and Motility Society and the Asian Neurogastroenterology and Motility Association, launched in January 2010 after the title change from the Korean Journal of Neurogastroenterology and Motility, published from 1994 to 2009.
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