Variations on the theme: focus on cerebellum and emotional processing.

IF 3.1 4区医学 Q2 NEUROSCIENCES

Frontiers in Systems Neuroscience Pub Date : 2023-05-10 eCollection Date: 2023-01-01 DOI:10.3389/fnsys.2023.1185752

Camilla Ciapponi, Yuhe Li, Dianela A Osorio Becerra, Dimitri Rodarie, Claudia Casellato, Lisa Mapelli, Egidio D'Angelo

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引用次数: 0

Abstract

The cerebellum operates exploiting a complex modular organization and a unified computational algorithm adapted to different behavioral contexts. Recent observations suggest that the cerebellum is involved not just in motor but also in emotional and cognitive processing. It is therefore critical to identify the specific regional connectivity and microcircuit properties of the emotional cerebellum. Recent studies are highlighting the differential regional localization of genes, molecules, and synaptic mechanisms and microcircuit wiring. However, the impact of these regional differences is not fully understood and will require experimental investigation and computational modeling. This review focuses on the cellular and circuit underpinnings of the cerebellar role in emotion. And since emotion involves an integration of cognitive, somatomotor, and autonomic activity, we elaborate on the tradeoff between segregation and distribution of these three main functions in the cerebellum.

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主题变奏：关注小脑和情绪处理。

小脑利用复杂的模块化组织和统一的计算算法进行运作，以适应不同的行为背景。最近的观察表明，小脑不仅参与运动，还参与情绪和认知处理。因此，确定情感小脑的特定区域连接和微电路特性至关重要。最近的研究凸显了基因、分子、突触机制和微电路线路的区域定位差异。然而，这些区域差异的影响尚不完全清楚，需要进行实验研究和计算建模。本综述将重点关注小脑在情绪中作用的细胞和电路基础。由于情绪涉及认知、躯体运动和自主神经活动的整合，我们将详细阐述这三大功能在小脑中的分离和分布之间的权衡。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Frontiers in Systems Neuroscience Neuroscience-Developmental Neuroscience

CiteScore

6.00

自引率

3.30%

发文量

144

审稿时长

14 weeks

期刊介绍： Frontiers in Systems Neuroscience publishes rigorously peer-reviewed research that advances our understanding of whole systems of the brain, including those involved in sensation, movement, learning and memory, attention, reward, decision-making, reasoning, executive functions, and emotions.