[Chromatographic analysis of hard tooth tissue to determine the age of personality].

Q4 Medicine
P S Velenko, M P Poletaeva, A A Bychkov, D A Sheptulin, E A Gavrilova
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引用次数: 0

Abstract

The biochemical approach for age assessment is most appropriate in forensic medicine, as racemization of aspartic acid in bones and teeth is closely related to human biological age. The aim of the study is to assess the biochemical parameters of aspartic acid in human teeth, which can be implemented into forensic practice in Russia. Samples of dentin in amount of 20, taken from the teeth of subjects aged between 16 and 76, were examined. Chromatographic analysis of the samples was performed on a gas chromatograph using chiral column. Statistical data processing showed that the relative squared peak of D-aspartic acid has a strong correlation with human biological age. Data, obtained from the Russian population study, demonstrate the applicability of chromatography for forensic purposes. It should be noted that the approach to the racemization rate estimation in the hard tooth tissue was performed using standard laboratory equipment, which allows to easily implement this method in forensic medical practice.

【硬牙组织色谱分析确定人格年龄】。
由于天冬氨酸在骨骼和牙齿中的外消旋作用与人类的生物年龄密切相关,因此生物化学方法最适合用于法医学。该研究的目的是评估人类牙齿中天冬氨酸的生化参数,这可以在俄罗斯的法医实践中实施。从16岁至76岁的受试者的牙齿上提取了20个牙本质样本,进行了检查。采用手性柱气相色谱仪对样品进行色谱分析。统计数据处理表明,d -天冬氨酸相对平方峰与人体生物年龄有很强的相关性。从俄罗斯人口研究中获得的数据证明了色谱法在法医目的中的适用性。值得注意的是,硬牙组织中外消旋率估计的方法是使用标准的实验室设备进行的,这使得在法医实践中很容易实施该方法。
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来源期刊
Sudebno-Meditsinskaya Ekspertisa
Sudebno-Meditsinskaya Ekspertisa Medicine-Pathology and Forensic Medicine
CiteScore
0.60
自引率
0.00%
发文量
70
期刊介绍: The journal is concerned with the theory and practice of forensic medicine - the problems of thanatology, traumatology, toxicology, serology, forensic obstetrics, forensic dentistry, forensic psychiatry, forensic chemistry, physicotechnical methods of investigation, history of forensic medicine and some problems of criminology and legal laws related to forensic medicine. It publishes original studies by Russian authors, casuistry surveys, abstracts and reviews of Russian and foreign literature, scientific information, reports on scientific conferences.
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