The Prevalence and Risk Factors of Contralateral Cranial Cruciate Ligament Rupture in Medium-to-Large (≥15kg) Breed Dogs 8 Years of Age or Older.

IF 1 2区 农林科学 Q3 VETERINARY SCIENCES
Christina L Murphy, Jacqui Niles, Robert M Radasch
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引用次数: 0

Abstract

Objective:  The aim of this study was to determine the prevalence of contralateral cranial cruciate ligament rupture (CCLR) in dogs 8 years of age or older, weighing more than or equal to 15 kg at the time of first-side CCLR and to assess associated risks.

Study design:  It is a cross-sectional retrospective study of 831 client-owned dogs METHODS:  Medical records of dogs weighing more than or equal to 15 kgs that were more than or equal to 8 years of age at the time of first CCLR diagnosis were reviewed. Data collected included weight, sex, pre-operative tibial plateau angle, co-morbidities, time between diagnosis of first CCLR and diagnosis of contralateral CCLR. Multivariate logistic regression analysis was used to estimate odds ratio. A median follow-up period of over 112.7 months (25th/75th quartiles 75.4/157.7 months) from first CCLR diagnosis was allotted.

Results:  Eight-hundred thirty-one dogs were identified and included. About 19.1% (159/831 dogs, 95% confidence interval: 16.6-22.0%) of dogs that experience a first-side CCLR at 8 years of age or older will rupture the contralateral side, a median of 12.9 months (25th/75th quartiles 6.5/24.3 months) later. Age (p = 0.003) and breed, Golden Retrievers (p = 0.028) and Labrador Retrievers (p = 0.007), were factors significantly associated with contralateral CCLR.

Clinical relevance:  The prevalence of contralateral CCLR in medium-to-large breed dogs more than or equal to 8 years of age old is less than previously reported and the risk decreases as they age. This important information will help guide owners when deciding to pursue surgical stifle stabilization following CCLR in older dogs.

8 岁或以上中大型犬(≥15 千克)对侧颅骨十字韧带断裂的发生率和风险因素。
研究目的本研究旨在确定8岁或8岁以上、首侧颅交叉韧带断裂(CCLR)时体重大于或等于15千克的犬中对侧颅交叉韧带断裂(CCLR)的发生率,并评估相关风险:研究设计:这是一项横断面回顾性研究,研究对象为 831 只客户饲养的狗 方法:对首次诊断为 CCLR 时年龄大于或等于 8 岁、体重大于或等于 15 千克的狗的医疗记录进行审查。收集的数据包括体重、性别、术前胫骨平台角度、合并疾病、首次诊断 CCLR 与诊断对侧 CCLR 之间的时间间隔。多变量逻辑回归分析用于估算几率。自首次诊断 CCLR 起,中位随访时间超过 112.7 个月(第 25/75 四分位数为 75.4/157.7 个月):共鉴定并纳入了 831 只犬。在 8 岁或 8 岁以上发生第一侧 CCLR 的狗中,约有 19.1%(159/831 只,95% 置信区间:16.6-22.0%)的狗会在 12.9 个月(第 25/75 四分位数 6.5/24.3 个月)后发生对侧破裂。年龄(p = 0.003)和品种(金毛寻回猎犬(p = 0.028)和拉布拉多寻回猎犬(p = 0.007))是与对侧 CCLR 显著相关的因素:临床意义:年龄大于或等于 8 岁的中大型犬对侧 CCLR 的患病率低于之前的报道,而且随着年龄的增长,患病风险会降低。这一重要信息将有助于指导饲养者在决定对年长犬只进行 CCLR 后的跗关节稳定手术。
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来源期刊
CiteScore
2.00
自引率
15.40%
发文量
49
审稿时长
18-36 weeks
期刊介绍: Veterinary and Comparative Orthopaedics and Traumatology (VCOT) is the most important single source for clinically relevant information in orthopaedics and neurosurgery available anywhere in the world today. It is unique in that it is truly comparative and there is an unrivalled mix of review articles and basic science amid the information that is immediately clinically relevant in veterinary surgery today.
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