Population data and phylogenetic analysis of 37 Y-STR loci in the Hui population from Yunnan Province, Southwest China.

IF 1.2 4区医学 Q2 ANTHROPOLOGY

Annals of Human Biology Pub Date : 2023-02-01 DOI:10.1080/03014460.2023.2188258

Xiufeng Zhang, Kunya Li, Yifan Duan

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引用次数: 0

Abstract

Background: Previous studies of the genetic polymorphism of the Y-chromosomal short tandem repeat (Y-STR) of Huis were focussed on the northwest of China. However, the population genetic characteristics of Chinese Hui residing in Yunnan province, Southwest China, remain unclear.

Aim: To provide genetic data for 37 Y-STRs in the Chinese Hui population of Yunnan province, as well as to investigate population genetic relationships between the Chinese Hui and another 26 populations from China and neighbouring countries.

Subjects and methods: In total, 326 unrelated healthy male individuals were genotyped using the Goldeneye^TM Y Plus PCR Amplification Kit. Genetic relationships between different populations were analysed using YHRD's AMOVA tools.

Results: A total of 279 haplotypes were detected, out of which 244 were unique. The overall haplotype diversity (HD) and discrimination capacity (DC) were 0.9989 and 0.8611, respectively. The gene diversity (GD) ranged from 0.0544 (DYS645) to 0.9656 (DYS385).

Conclusions: The population comparison indicated that Muslim populations (Hui, Salar and Uighur) showed significantly more genetic affinity than other populations. Our results could be applied in forensic practice and population genetic studies.

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云南回族37个Y-STR基因座的种群资料及系统发育分析

背景:以往对回族人y染色体短串联重复序列(Y-STR)遗传多态性的研究主要集中在中国西北地区。然而，居住在中国西南部云南省的中国回族群体遗传特征尚不清楚。目的:提供云南省中国回族37个y - str的遗传资料，探讨中国回族与中国及周边地区26个人群的群体遗传关系。对象和方法:使用GoldeneyeTM Y + PCR扩增试剂盒对326名无亲缘关系的健康男性进行基因分型。利用YHRD的AMOVA工具分析了不同群体间的遗传关系。结果:共检测到279个单倍型，其中244个是唯一的。总单倍型多样性(HD)和鉴别能力(DC)分别为0.9989和0.8611。基因多样性(GD)范围为0.0544 (DYS645) ~ 0.9656 (DYS385)。结论:穆斯林人群(回族、撒拉族和维吾尔族)的遗传亲和力明显高于其他人群。我们的研究结果可以应用于法医实践和群体遗传学研究。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Annals of Human Biology 生物-公共卫生、环境卫生与职业卫生

CiteScore

3.40

自引率

5.90%

发文量

审稿时长

1 months

期刊介绍： Annals of Human Biology is an international, peer-reviewed journal published six times a year in electronic format. The journal reports investigations on the nature, development and causes of human variation, embracing the disciplines of human growth and development, human genetics, physical and biological anthropology, demography, environmental physiology, ecology, epidemiology and global health and ageing research.