Leptin and male fertility: unraveling the molecular pathways, receptor functions, and therapeutic potential.

IF 12.8 1区医学 Q1 BIOCHEMISTRY & MOLECULAR BIOLOGY

Trends in molecular medicine Pub Date : 2023-11-01 Epub Date: 2023-07-21 DOI:10.1016/j.molmed.2023.06.010

Himanshu Arora

引用次数: 0

Abstract

Leptin, an adipokine hormone, is a critical regulator of energy homeostasis, appetite, and metabolism. Recent advances have elucidated its role in male fertility. This forum provides an overview of the interplay between leptin, its receptors, and signaling pathways in the context of male fertility, revealing its multifaceted impact on reproductive health.

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瘦素与男性生育能力：揭示分子途径、受体功能和治疗潜力。

瘦素是一种脂肪因子激素，是能量稳态、食欲和代谢的关键调节因子。最近的进展阐明了它在男性生育中的作用。该论坛概述了瘦素及其受体和男性生育过程中信号通路之间的相互作用，揭示了其对生殖健康的多方面影响。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Trends in molecular medicine 医学-生化与分子生物学

CiteScore

24.60

自引率

0.00%

发文量

142

审稿时长

6-12 weeks

期刊介绍： Trends in Molecular Medicine (TMM) aims to offer concise and contextualized perspectives on the latest research advancing biomedical science toward better diagnosis, treatment, and prevention of human diseases. It focuses on research at the intersection of basic biology and clinical research, covering new concepts in human biology and pathology with clear implications for diagnostics and therapy. TMM reviews bridge the gap between bench and bedside, discussing research from preclinical studies to patient-enrolled trials. The major themes include disease mechanisms, tools and technologies, diagnostics, and therapeutics, with a preference for articles relevant to multiple themes. TMM serves as a platform for discussion, pushing traditional boundaries and fostering collaboration between scientists and clinicians. The journal seeks to publish provocative and authoritative articles that are also accessible to a broad audience, inspiring new directions in molecular medicine to enhance human health.