Human adenoviruses: A suspect behind the outbreak of acute hepatitis in children amid the COVID-19 pandemic

Hongyun Wang , Shimin Yang , Jiejie Liu , Zhiying Fu , Yingle Liu , Li Zhou , Haitao Guo , Ke Lan , Yu Chen
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引用次数: 3

Abstract

As of 10 May 2022, at least 450 cases of pediatric patients with acute hepatitis of unknown cause have been reported worldwide. Human adenoviruses (HAdVs) have been detected in at least 74 cases, including the F type HAdV41 in 18 cases, which indicates that adenoviruses may be associated with this mysterious childhood hepatitis, although other infectious agents or environmental factors cannot be excluded. In this review, we provide a brief introduction of the basic features of HAdVs and describe diseases caused by different HAdVs in humans, aiming to help understand the biology and potential risk of HAdVs and cope with the outbreak of acute child hepatitis.

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人类腺病毒:新冠肺炎大流行期间儿童急性肝炎爆发的幕后嫌疑人。
截至2022年5月10日,全球已报告至少450例不明原因急性肝炎患儿。在至少74例病例中检测到人类腺病毒(HAdVs),包括18例中的F型HAdV41,这表明腺病毒可能与这种神秘的儿童肝炎有关,尽管不能排除其他传染源或环境因素。在这篇综述中,我们简要介绍了HAdV的基本特征,并描述了由不同的HAdV在人类中引起的疾病,旨在帮助了解HAdVs的生物学和潜在风险,并应对急性儿童肝炎的爆发。
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来源期刊
Cell insight
Cell insight Neuroscience (General), Biochemistry, Genetics and Molecular Biology (General), Cancer Research, Cell Biology
CiteScore
2.70
自引率
0.00%
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0
审稿时长
35 days
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