CoronaVac vaccine does not affect ovarian reserve.

IF 1.2 4区医学 Q3 OBSTETRICS & GYNECOLOGY

Ginekologia polska Pub Date : 2023-01-01 DOI:10.5603/GP.a2023.0025

Ayşe Rabia Şenkaya, Zafer Çil, Ömür Keskin, Mehmet Emin Güneş, Deniz Can Öztekin

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引用次数: 2

Abstract

Objectives: In this study, our aim is to investigate the effect of CoronaVac vaccine on ovarian reserve in female patients followed up for infertility.

Material and methods: Our study is a retrospective study. Forty-six infertile patients who received two doses of CoronaVac vaccine one month apart and had not had a previous Covid 19 infection were included in the study. Anti-müllerian hormone (AMH) and folliculometry of 46 patients one month before CoronaVac vaccine and one month after the second dose of vaccine were compared.

Results: There was no statistically significant difference in the change of AMH level and follicle number before and after vaccination (respectively p = 0.366; 0.610).

Conclusions: Considering that having a COVID-19 infection has a negative effect on female fertility and causing ovarian damage in recent studies, vaccination is a rational and cost-effective approach to protect ovarian reserve. Knowing that the vaccine does not have a negative effect on fertility may increase the application of the vaccine in women of reproductive age.

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冠状病毒疫苗不影响卵巢储备。

目的:在本研究中，我们的目的是探讨冠状静脉注射疫苗对女性不孕症患者卵巢储备的影响。材料与方法:本研究为回顾性研究。这项研究包括46名不孕患者，他们间隔一个月接种了两剂冠状病毒疫苗，之前没有感染过Covid - 19。比较46例患者在冠状病毒疫苗接种前1个月和第二次接种后1个月的抗勒氏杆菌激素(AMH)和卵泡测定。结果:接种前后AMH水平和卵泡数变化差异无统计学意义(p = 0.366;0.610)。结论:考虑到近期研究中COVID-19感染对女性生育能力的负面影响和卵巢损伤，接种疫苗是一种合理且经济有效的保护卵巢储备的方法。认识到疫苗对生育能力没有负面影响，可能会增加育龄妇女接种疫苗的数量。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Ginekologia polska OBSTETRICS & GYNECOLOGY-

CiteScore

2.00

自引率

15.40%

发文量

317

审稿时长

4-8 weeks

期刊介绍： Ginekologia Polska’ is a monthly medical journal published in Polish and English language. ‘Ginekologia Polska’ will accept submissions relating to any aspect of gynaecology, obstetrics and areas directly related. ‘Ginekologia Polska’ publishes original contributions, comparative works, case studies, letters to the editor and many other categories of articles.