The Effects of Light Therapy on Sleep, Agitation and Depression in People With Dementia: A Systematic Review and Meta-analysis of Randomized Controlled Trials.

IF 2.7 4区医学 Q2 CLINICAL NEUROLOGY

American Journal of Alzheimers Disease and Other Dementias Pub Date : 2023-01-01 DOI:10.1177/15333175231160682

Kenneth Nk Fong, Xiangyang Ge, K H Ting, Minchen Wei, Hilda Cheung

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引用次数: 0

Abstract

Objective: To evaluate the effects of light therapy on the alleviation of sleep disturbances, agitation and depression in people with dementia.

Methods: A search was performed in PubMed, Medline, SCOPUS, Web of Science, EMBASE, CINAHL, Cochrane Library, for studies published between 2000 and 2021.

Results: A total of 4315 articles were screened. Sixteen articles were eligible for this review and 11 randomized controlled studies were included in the meta-analysis. Light therapy had a significant effect on reducing the number of awakenings in sleep (n = 4; 95% CI = -.56, -.05; I² = 0%; SMD = -.31) but was not significant in reducing the wake after sleep onset (n = 3; 95% CI = -.14, .59; I² = 0%; SMD = .23), agitation (n = 4; 95% CI = -1.02, .45; I² = 87%; SMD = -.28) and depression (n = 6; 95% CI = -.80, .40, I² = 85%; SMD = -.20).

Conclusion: Light therapy appeared to be more effective in terms of alleviating sleep disturbances, rather than reducing agitation and depression, but its long-term effects remain unclear.

查看原文本刊更多论文

光疗对痴呆症患者睡眠、躁动和抑郁的影响：随机对照试验的系统回顾与元分析》。

目的：评估光疗对缓解痴呆症患者睡眠障碍、躁动和抑郁的效果：评估光疗对缓解痴呆症患者睡眠障碍、躁动和抑郁的效果：方法：在 PubMed、Medline、SCOPUS、Web of Science、EMBASE、CINAHL 和 Cochrane Library 中检索 2000 年至 2021 年间发表的研究：结果：共筛选出 4315 篇文章。结果：共筛选出 4315 篇文章，其中 16 篇符合综述条件，11 项随机对照研究被纳入荟萃分析。光疗对减少睡眠中的觉醒次数有显著效果（n = 4；95% CI = -.56, -.05；I2 = 0%；SMD = -.31），但对减少睡眠开始后的觉醒次数没有显著效果（n = 3；95% CI = -.14，.59；I2 = 0%；SMD = .23）、躁动（n = 4；95% CI = -1.02, .45；I2 = 87%；SMD = -.28）和抑郁（n = 6；95% CI = -.80, .40，I2 = 85%；SMD = -.20）：光疗在缓解睡眠障碍方面似乎比减少躁动和抑郁更有效，但其长期效果仍不明确。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

American Journal of Alzheimers Disease and Other Dementias GERIATRICS & GERONTOLOGY-CLINICAL NEUROLOGY

CiteScore

5.40

自引率

0.00%

发文量

审稿时长

6-12 weeks

期刊介绍： American Journal of Alzheimer''s Disease and other Dementias® (AJADD) is for professionals on the frontlines of Alzheimer''s care, dementia, and clinical depression--especially physicians, nurses, psychiatrists, administrators, and other healthcare specialists who manage patients with dementias and their families. This journal is a member of the Committee on Publication Ethics (COPE).