Survival, Incidence, and Mortality Trends in Female Cancers in the Nordic Countries.

IF 1.6 Q3 OBSTETRICS & GYNECOLOGY
Filip Tichanek, Asta Försti, Otto Hemminki, Akseli Hemminki, Kari Hemminki
{"title":"Survival, Incidence, and Mortality Trends in Female Cancers in the Nordic Countries.","authors":"Filip Tichanek,&nbsp;Asta Försti,&nbsp;Otto Hemminki,&nbsp;Akseli Hemminki,&nbsp;Kari Hemminki","doi":"10.1155/2023/6909414","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Female cancers cover common breast cancers, relatively common endometrial, ovarian, and cervical cancers and rare vulvar cancer. Survival in these cancers is known to be relatively good compared to all cancers but long-term studies for these cancers are rare, and to fill the gap, here, we generate survival data through 50 years.</p><p><strong>Materials and methods: </strong>We applied generalized additive models to data from the NORDCAN database and analyzed 1- and 5-year relative survival for these cancers in Denmark (DK), Finland (FI), Norway (NO), and Sweden (SE) over half a century (1971-2020). Conditional 5/1-year survival for patients who survived the 1st year after diagnosis and annual survival changes was also estimated.</p><p><strong>Results: </strong>In 2016-20, 5-year survival was best for breast cancer reaching 92.3% (in SE), followed by endometrial cancer at 86.1% (SE) and cervical cancer at 75.6% (NO). Improvement in 5-year survival over the 50 years was the largest for ovarian cancer (20% units), finally reaching 52.9% (SE). For vulvar cancer, the final survival was between 70 and 73%. The best 5-year survival rate in 2016-20 was recorded for SE in breast, endometrial, and ovarian cancers; NO showed the highest rate for cervical and DK for vulvar cancers. DK had the lowest survival for breast and ovarian cancers, and FI, for the other cancers.</p><p><strong>Conclusions: </strong>The overall survival development appeared to consist of continuous improvements, most likely because of novel treatment and imaging techniques as well as overall organization of patient care. The large survival improvement for ovarian cancer was probably achieved by a surgical focus on tumors spread in the peritoneal cavity. For cervical and vulvar cancers, the high early mortality requires attention and could be helped by raising increasing public awareness of early symptoms in these cancers and developing pathways for fast initiation of treatment.</p>","PeriodicalId":19439,"journal":{"name":"Obstetrics and Gynecology International","volume":null,"pages":null},"PeriodicalIF":1.6000,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10348860/pdf/","citationCount":"1","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Obstetrics and Gynecology International","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1155/2023/6909414","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"OBSTETRICS & GYNECOLOGY","Score":null,"Total":0}
引用次数: 1

Abstract

Background: Female cancers cover common breast cancers, relatively common endometrial, ovarian, and cervical cancers and rare vulvar cancer. Survival in these cancers is known to be relatively good compared to all cancers but long-term studies for these cancers are rare, and to fill the gap, here, we generate survival data through 50 years.

Materials and methods: We applied generalized additive models to data from the NORDCAN database and analyzed 1- and 5-year relative survival for these cancers in Denmark (DK), Finland (FI), Norway (NO), and Sweden (SE) over half a century (1971-2020). Conditional 5/1-year survival for patients who survived the 1st year after diagnosis and annual survival changes was also estimated.

Results: In 2016-20, 5-year survival was best for breast cancer reaching 92.3% (in SE), followed by endometrial cancer at 86.1% (SE) and cervical cancer at 75.6% (NO). Improvement in 5-year survival over the 50 years was the largest for ovarian cancer (20% units), finally reaching 52.9% (SE). For vulvar cancer, the final survival was between 70 and 73%. The best 5-year survival rate in 2016-20 was recorded for SE in breast, endometrial, and ovarian cancers; NO showed the highest rate for cervical and DK for vulvar cancers. DK had the lowest survival for breast and ovarian cancers, and FI, for the other cancers.

Conclusions: The overall survival development appeared to consist of continuous improvements, most likely because of novel treatment and imaging techniques as well as overall organization of patient care. The large survival improvement for ovarian cancer was probably achieved by a surgical focus on tumors spread in the peritoneal cavity. For cervical and vulvar cancers, the high early mortality requires attention and could be helped by raising increasing public awareness of early symptoms in these cancers and developing pathways for fast initiation of treatment.

Abstract Image

Abstract Image

Abstract Image

北欧国家女性癌症的生存、发病率和死亡率趋势。
背景:女性癌症包括常见的乳腺癌、相对常见的子宫内膜癌、卵巢癌和宫颈癌以及罕见的外阴癌。与所有癌症相比,这些癌症的存活率相对较好但对这些癌症的长期研究很少,为了填补这一空白,我们生成了50年的生存数据。材料和方法:我们将广义相加模型应用于NORDCAN数据库的数据,并分析了丹麦(DK)、芬兰(FI)、挪威(NO)和瑞典(SE)半个多世纪(1971-2020)这些癌症的1年和5年相对生存率。诊断后1年存活的患者的条件5/1年生存率和年度生存变化也被估计。结果:2016- 2020年,乳腺癌的5年生存率最高,为92.3% (In SE),其次是子宫内膜癌(86.1%)和宫颈癌(75.6%)。50年5年生存率改善最大的是卵巢癌(20%单位),最终达到52.9% (SE)。对于外阴癌,最终存活率在70%到73%之间。2016- 2020年,乳腺癌、子宫内膜癌和卵巢癌的SE患者的5年生存率最高;NO在宫颈癌和DK在外阴癌中发病率最高。乳腺癌和卵巢癌的DK生存率最低,其他癌症的生存率最低。结论:总体生存发展似乎包括持续改善,很可能是因为新的治疗和成像技术以及患者护理的整体组织。卵巢癌生存率的大幅提高可能是由于对扩散到腹膜腔的肿瘤进行手术治疗。对于子宫颈癌和外阴癌,高早期死亡率需要引起注意,提高公众对这些癌症早期症状的认识,并制定快速开始治疗的途径,可以帮助解决这一问题。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
Obstetrics and Gynecology International
Obstetrics and Gynecology International OBSTETRICS & GYNECOLOGY-
CiteScore
3.60
自引率
0.00%
发文量
26
审稿时长
19 weeks
期刊介绍: Obstetrics and Gynecology International is a peer-reviewed, Open Access journal that aims to provide a forum for scientists and clinical professionals working in obstetrics and gynecology. The journal publishes original research articles, review articles, and clinical studies related to obstetrics, maternal-fetal medicine, general gynecology, gynecologic oncology, uro-gynecology, reproductive medicine and infertility, reproductive endocrinology, and sexual medicine.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信