Y-STR data of the Yfiler Plus panel in population of north-eastern Poland.

Q4 Medicine

Archiwum Medycyny Sadowej i Kryminologii Pub Date : 2022-01-01 DOI:10.4467/16891716AMSIK.22.022.17622

Agnieszka Gołaszewska, Małgorzata Skawrońska, Anna Niemcunowicz-Janica, Witold Pepiński

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引用次数: 0

Abstract

Background: The use of new high-resolution and forensic identification capabilities for population studies offered by new multiplex methods (such as Yfiler Plus) is crucial in forensic genetics cases. The development of haplotype frequency databases is essential to take full advantage of the new Y chromosome determination capabilities.

Purpose: Development of the haplotype database of the Yfiler Plus kit for a population-based sample of 534 males from northeastern Poland and calculation of suitability parameters for forensic genetics studies.

Materials and methods: The study was conducted on a population sample of 534 unrelated males from the area of northeastern Poland using the Yfiler Plus panel of 27 markers located on the Y chromosome.

Results: Four haplotypes appeared twice. The Discrimination Capacity (DC) of the entire set was 0.9925. The highest Gene Diversity (GD) value was calculated for DYS518 (0.86) belonging to the fast-mutation markers, while the lowest GD was calculated for DYS392 (0.42).

Conclusion: The results indicate the need for further research and observation of changes, both in different regions of Poland and across Europe.

查看原文本刊更多论文

波兰东北部人口Yfiler Plus面板的Y-STR数据。

背景:利用新的多重方法(如Yfiler Plus)为人口研究提供的新的高分辨率和法医鉴定能力在法医遗传学案件中至关重要。单倍型频率数据库的开发是充分利用新的Y染色体测定能力的必要条件。目的:为波兰东北部534名男性人群样本建立Yfiler Plus试剂盒的单倍型数据库，并计算法医遗传学研究的适宜性参数。材料和方法:本研究采用位于Y染色体上的27个标记的Yfiler Plus面板，对来自波兰东北部地区的534名无亲缘关系的男性进行了人口样本研究。结果:4个单倍型出现两次。整个集合的判别能力(DC)为0.9925。快速突变标记DYS518的基因多样性(GD)值最高，为0.86,DYS392的GD值最低，为0.42。结论:结果表明，需要进一步研究和观察波兰不同地区和整个欧洲的变化。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Archiwum Medycyny Sadowej i Kryminologii Medicine-Medicine (all)

CiteScore

0.60

自引率

0.00%

发文量

审稿时长

12 weeks

期刊介绍： Archiwum Medycyny Sądowej i Kryminologii przyjmuje w języku polskim: prace doświadczalne, poglądowe, kazuistyczne, artykuły o charakterze szkoleniowym z medycyny sądowej, kryminologii i dziedzin pokrewnych, opracowania z zakresu etyki i deontologii lekarskiej, streszczenia prac obcych, oceny książek, sprawozdania z działalności PTMSiK, sprawozdania ze zjazdów krajowych i zagranicznych, komunikaty Zarządu Głównego PTMSiK, listy do Redakcji. Autor powinien podać, do jakiej kategorii zalicza tekst nadesłanej pracy. Przyjmowane do druku będą również prace autorów zagranicznych w języku angielskim.