Donor-recipient matching in adult liver transplantation: Current status and advances.

IF 5.7 4区 生物学 Q1 BIOLOGY
Caterina Accardo, Ivan Vella, Duilio Pagano, Fabrizio di Francesco, Sergio Li Petri, Sergio Calamia, Pasquale Bonsignore, Alessandro Tropea, Salvatore Gruttadauria
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引用次数: 0

Abstract

The match between donor and recipient (D-R match) in the field of liver transplantation (LT) is one of the most widely debated topics today. Within the cohort of patients waiting for a transplant, better matching of the donor organ to the recipient will improve transplant outcomes, and benefit the waiting list by minimizing graft failure and the need for re-transplantation. In an era of suboptimal matches due to the sparse organ pool and the increase in extended criteria donors (ECD), ensuring adequate outcomes becomes the primary goal for clinicians in the field. The objective of this mini-review is to analyze the main variables in the evaluation of the D-R match to ensure better outcomes, the existence of scores that can help in the realization of this match, and the latest advances made thanks to the technology and development of artificial intelligence (AI).

成人肝移植供体-受体匹配的现状与进展。
肝移植中供体与受体之间的匹配(D-R match)是目前争论最广泛的话题之一。在等待移植的患者队列中,供体器官与受体更好的匹配将改善移植结果,并通过减少移植失败和再次移植的需要而使等待名单受益。在一个由于器官池稀疏和扩展标准供体(ECD)增加而导致匹配不理想的时代,确保足够的结果成为该领域临床医生的主要目标。这篇迷你综述的目的是分析D-R比赛评估中的主要变量,以确保更好的结果,有助于实现这一比赛的分数的存在,以及由于人工智能(AI)技术和发展而取得的最新进展。
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来源期刊
CiteScore
13.60
自引率
1.80%
发文量
47
审稿时长
>12 weeks
期刊介绍: BioScience Trends (Print ISSN 1881-7815, Online ISSN 1881-7823) is an international peer-reviewed journal. BioScience Trends devotes to publishing the latest and most exciting advances in scientific research. Articles cover fields of life science such as biochemistry, molecular biology, clinical research, public health, medical care system, and social science in order to encourage cooperation and exchange among scientists and clinical researchers.
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