Genital ulcers following all-trans-retinoic acid therapy: A case series with review of literature.

IF 1.4 4区医学 Q4 PHARMACOLOGY & PHARMACY

Indian Journal of Pharmacology Pub Date : 2023-03-01 DOI:10.4103/ijp.ijp_811_21

Neerja Saraswat, Sushil Kumar, Rahul Prem, Durga Madhab Tripathi

引用次数: 0

Abstract

All-trans-retinoic acid (ATRA) has transformed the treatment of acute promyelocytic leukemia. Most of the adverse effects associated with this drug are minor barring differentiation syndromes. Genital ulcers feature among the underreported adverse effects of ATRA which needs to be kept in mind to avoid life-threatening complications. We describe two cases who developed genital ulcers while treated with ATRA.

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全反式维甲酸治疗后的生殖器溃疡:一个病例系列与文献回顾。

全反式维甲酸(ATRA)已经改变了急性早幼粒细胞白血病的治疗方法。与该药相关的大多数不良反应是轻微的阻断证。生殖器溃疡是ATRA未被报道的不良反应之一，需要牢记这一点，以避免危及生命的并发症。我们描述了两个病例谁发展生殖器溃疡而与ATRA治疗。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Indian Journal of Pharmacology 医学-药学

CiteScore

4.00

自引率

4.20%

发文量

审稿时长

4-8 weeks

期刊介绍： Indian Journal of Pharmacology accepts, in English, review articles, articles for educational forum, original research articles (full length and short communications), letter to editor, case reports and interesting fillers. Articles concerning all aspects of pharmacology will be considered. Articles of general interest (e.g. methods, therapeutics, medical education, interesting websites, new drug information and commentary on a recent topic) are also welcome.