Differential trend of mild and severe preeclampsia among nulliparous women: a population-based study of South Korea.

IF 2 Q2 OBSTETRICS & GYNECOLOGY

Obstetrics and Gynecology Science Pub Date : 2023-09-01 Epub Date: 2023-06-29 DOI:10.5468/ogs.23033

Seyoung Kim, Ji Yeon Lee, Tammie Kim, Eunseon Gwak, Seung-Ah Choe

引用次数: 0

Abstract

We explored the annual risks of mild and severe preeclampsia (PE) among nulliparous women. Using the National Health Information Database of South Korea, 1,317,944 nulliparous women who gave live births were identified. Mild PE increased from 0.9% in 2010 to 1.4% in 2019 (P for trend=0.006), while severe PE decreased from 0.4% in 2010 to 0.3% in 2019 (P=0.049). The incidence of all types of PE (mild and severe) showed no linear change (P=0.514). Adjusted odds ratio (OR) of severe PE decreased in 2013 (0.68; 95% confidence interval [CI]: 0.60, 0.77) and beyond compared to that in 2010, while the OR of mild PE increased in 2017 (1.14; 95% CI: 1.06, 1.22) and beyond. Mild PE was found to be less likely to progress to the severe form since 2010; however, the overall risk of PE among women did not change.

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未产妇轻度和重度先兆子痫的差异趋势：一项基于韩国人群的研究。

我们探讨了未产妇中轻度和重度先兆子痫（PE）的年度风险。利用韩国国家健康信息数据库，确定了1317944名活产未产妇。轻度PE从2010年的0.9%上升到2019年的1.4%（趋势P=0.006），而重度PE从2010的0.4%下降到2019的0.3%（P=0.049）。所有类型的PE（轻度和重度）的发病率都没有线性变化（P=0.514）。与2010年相比，2013年重度PE的调整后比值比（OR）下降（0.68；95%置信区间[CI]:0.60，0.77）及以上，而轻度PE的OR在2017年及以后增加（1.14；95%CI:1.061.22）。自2010年以来，轻度PE发展为严重PE的可能性较小；然而，女性患PE的总体风险没有改变。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Obstetrics and Gynecology Science Medicine-Obstetrics and Gynecology

CiteScore

3.80

自引率

15.80%

发文量

审稿时长

16 weeks

期刊介绍： Obstetrics & Gynecology Science (NLM title: Obstet Gynecol Sci) is an international peer-review journal that published basic, translational, clinical research, and clinical practice guideline to promote women’s health and prevent obstetric and gynecologic disorders. The journal has an international editorial board and is published in English on the 15th day of every other month. Submitted manuscripts should not contain previously published material and should not be under consideration for publication elsewhere. The journal has been publishing articles since 1958. The aim of the journal is to publish original articles, reviews, case reports, short communications, letters to the editor, and video articles that have the potential to change the practices in women''s health care. The journal’s main focus is the diagnosis, treatment, prediction, and prevention of obstetric and gynecologic disorders. Because the life expectancy of Korean and Asian women is increasing, the journal''s editors are particularly interested in the health of elderly women in these population groups. The journal also publishes articles about reproductive biology, stem cell research, and artificial intelligence research for women; additionally, it provides insights into the physiology and mechanisms of obstetric and gynecologic diseases.