Anastomotic Ulcers: Current Understanding of the Pathogenesis and Management.

Q1 Medicine
Shaunte McKay, Valeria Cohran, Lee M Bass
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引用次数: 0

Abstract

Purpose of review: Anastomotic ulceration following intestinal resection is an under- recognized problem in pediatrics. We discuss the relevant literature regarding this condition.

Recent findings: Anastomotic Ulceration following intestinal resection is a potentially life threatening cause of refractory anemia. Evaluation should include correction of micronutrient deficiencies and endoscopic evaluation by upper and lower endoscopy and small intestinal endoscopy if necessary. Initial treatment by medical therapy may consist of anti-inflammatory agents as well as antibiotics to treat small intestinal bacterial overgrowth. Surgical resection should be considered if refractory to treatment. Anastomotic ulcers in pediatric patients with small bowel resection should be considered as a cause of refractory iron deficiency anemia. Endoscopic evaluation should be undertaken to look for evidence of anastomotic ulcers. Surgical resection should be considered if medical therapy fails.

吻合口溃疡:目前对其发病机制和治疗的认识。
回顾目的:小肠切除术后吻合口溃疡是儿科一个未被充分认识的问题。我们讨论了有关这种情况的相关文献。近期发现:肠切除术后吻合口溃疡是难治性贫血的潜在威胁生命的原因。评估应包括微量营养素缺乏的纠正和内镜评估,如有必要,通过上下内镜和小肠内镜进行评估。药物治疗的初始治疗可能包括抗炎剂和抗生素,以治疗小肠细菌过度生长。如果难以治疗,应考虑手术切除。小儿小肠切除术后吻合口溃疡应被认为是难治性缺铁性贫血的原因之一。应进行内镜检查以寻找吻合口溃疡的证据。如果药物治疗失败,应考虑手术切除。
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来源期刊
Current Gastroenterology Reports
Current Gastroenterology Reports Medicine-Gastroenterology
CiteScore
7.80
自引率
0.00%
发文量
19
期刊介绍: As the field of gastroenterology and hepatology rapidly evolves, the wealth of published literature can be overwhelming. The aim of the journal is to help readers stay abreast of such advances by offering authoritative, systematic reviews by leading experts. We accomplish this aim by appointing Section Editors who invite international experts to contribute review articles that highlight recent developments and important papers published in the past year. Major topics in gastroenterology are covered, including pediatric gastroenterology, neuromuscular disorders, infections, nutrition, and inflammatory bowel disease. These reviews provide clear, insightful summaries of expert perspectives relevant to clinical practice. An Editorial Board of internationally diverse members suggests topics of special interest to their country/region and ensures that topics are current and include emerging research. We also provide commentaries from well-known figures in the field.
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