The Participation of Ca²⁺ Channels in Epilepsy: A Bibliometric Analysis of the Scientific Literature in Latin America.

IF 2.7 4区医学 Q3 NEUROSCIENCES

CNS & neurological disorders drug targets Pub Date : 2024-01-01 DOI:10.2174/1871527322666230518115952

Carmen Rubio, Noel Gallardo, Vanessa Mena, Alonso Portilla, Moisés Rubio-Osornio

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引用次数: 0

Abstract

Background: Bibliometric analysis allows us to quantify and evaluate scientific activity, and it has become increasingly important in all areas of scientific literature. Thanks to these analyses, we can infer where science should put greater efforts into elucidating the underlying mechanisms of diseases that have yet to be fully described or investigated.

Objective: This paper delves into published articles related to the involvement of calcium (Ca²⁺) channels in epilepsy, which is a condition with a high prevalence in Latin America.

Methods: We followed the scientific publication on SCOPUS and analyzed the impact of publications from Latin America in the field of epilepsy and the study of Ca²⁺ channels. We identified the countries with the largest number of publications and found that 68% of them were experimental (animal models), while 32% were clinical. We also identified the main journals, growth over time, and citation numbers.

Results: We found a total of 226 works produced by Latin American countries from 1976 to 2022. The countries that have contributed the most to the topic are Brazil, Mexico, and Argentina, with occasional collaborations between them to make contributions to the study of epilepsy and Ca²⁺ channels. Additionally, we found that the journal with the most citations is Nature Genetics.

Conclusion: The number of authors per article ranges from 1 to 242, and neuroscience journals are the preferred target for researchers, with a predilection for publishing original articles, although 26% of the publications are review articles.

查看原文本刊更多论文

Ca2+ 通道在癫痫中的参与：拉丁美洲科学文献的文献计量分析》。

背景：文献计量分析使我们能够量化和评估科学活动，它在科学文献的各个领域都变得越来越重要。通过这些分析，我们可以推断出科学界应在哪些方面加大力度，以阐明尚未得到充分描述或研究的疾病的内在机制：本文深入研究了与钙通道（Ca2+）参与癫痫病相关的已发表文章，癫痫病在拉丁美洲的发病率很高：我们跟踪了 SCOPUS 上的科学出版物，分析了拉丁美洲在癫痫和 Ca2+ 通道研究领域发表的出版物的影响力。我们确定了发表论文数量最多的国家，发现其中 68% 为实验性论文（动物模型），32% 为临床论文。我们还确定了主要期刊、随时间推移的增长情况以及引用次数：结果：我们发现，从 1976 年到 2022 年，拉丁美洲国家共发表了 226 篇论文。对这一主题贡献最大的国家是巴西、墨西哥和阿根廷，它们之间偶尔也会合作，为癫痫和 Ca2+ 通道的研究做出贡献。此外，我们还发现被引用次数最多的期刊是《自然-遗传学》：每篇文章的作者人数从 1 人到 242 人不等，神经科学期刊是研究人员的首选目标，偏向于发表原创文章，尽管有 26% 的出版物是综述文章。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

CNS & neurological disorders drug targets 医学-神经科学

CiteScore

5.10

自引率

3.30%

发文量

158

审稿时长

6-12 weeks

期刊介绍： Aims & Scope CNS & Neurological Disorders - Drug Targets aims to cover all the latest and outstanding developments on the medicinal chemistry, pharmacology, molecular biology, genomics and biochemistry of contemporary molecular targets involved in neurological and central nervous system (CNS) disorders e.g. disease specific proteins, receptors, enzymes, genes. CNS & Neurological Disorders - Drug Targets publishes guest edited thematic issues written by leaders in the field covering a range of current topics of CNS & neurological drug targets. The journal also accepts for publication original research articles, letters, reviews and drug clinical trial studies. As the discovery, identification, characterization and validation of novel human drug targets for neurological and CNS drug discovery continues to grow; this journal is essential reading for all pharmaceutical scientists involved in drug discovery and development.