The prevalence of IGM antibodies to Zika virus in pregnant women in Northern Nigeria.

Q3 Medicine

Voprosy virusologii Pub Date : 2023-05-18 DOI:10.36233/0507-4088-162

H A Adekola, D A Ojo, S A Balogun, M A Dipeolu, M Mohammed, D S Adejo, R M Aliyu, M A Abdullahi, N H Madugu

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引用次数: 0

Abstract

Introduction: Zika virus (ZIKV) infection during pregnancy can result in severe outcomes for both the pregnant woman and the developing fetus. The objective of this study was to investigate the prevalence of Zika virus infection among pregnant women who sought healthcare services at Ahmadu Bello University Teaching Hospital.

Materials and methods: Serum samples were collected and analyzed using Enzyme Linked Immunoassay and RT-qPCR methods, while a structured questionnaire was used to gather relevant information about the participants.

Results: The results showed that 53 out of the 180 pregnant women tested positive for Anti-Zika IgM antibodies, which represents a 29.4% prevalence rate. Subsequent RT-qPCR analysis found that only 6 out of the 53 positive samples contained Zika virus RNA. Fever and headache were the most commonly reported symptoms related to the infection.

Conclusion: These findings indicate a potential outbreak of Zika fever in Northern Nigeria emphasizing the importance for pregnant women to take precautions to avoid getting infected.

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尼日利亚北部孕妇寨卡病毒IGM抗体流行情况

妊娠期感染寨卡病毒(ZIKV)可对孕妇和发育中的胎儿造成严重后果。本研究的目的是调查在Ahmadu Bello大学教学医院寻求医疗服务的孕妇中寨卡病毒感染的流行情况。材料与方法:采用酶联免疫分析法和RT-qPCR法采集血清样本进行分析，同时采用结构化问卷收集参与者的相关信息。结果:180名孕妇中，53人的抗寨卡IgM抗体检测呈阳性，患病率为29.4%。随后的RT-qPCR分析发现，53个阳性样本中只有6个含有寨卡病毒RNA。发烧和头痛是与感染相关的最常见症状。结论:这些发现表明尼日利亚北部可能爆发寨卡热，强调孕妇采取预防措施以避免感染的重要性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Voprosy virusologii Medicine-Infectious Diseases

CiteScore

2.00

自引率

0.00%

发文量

期刊介绍： The journal deals with advances in virology in Russia and abroad. It publishes papers dealing with investigations of viral diseases of man, animals and plants, the results of experimental research on different problems of general and special virology. The journal publishes materials are which promote introduction into practice of the achievements of the virological science in the eradication and incidence reduction of infectious diseases, as well as their diagnosis, treatment and prevention. The reader will find a description of new methods of investigation, new apparatus and devices.