Left Atrial Dysfunction in Apical Hypertrophic Cardiomyopathy: Assessed by Cardiovascular Magnetic Resonance Feature-tracking.

IF 2 4区医学 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

Journal of Thoracic Imaging Pub Date : 2024-05-01 Epub Date: 2023-06-20 DOI:10.1097/RTI.0000000000000722

Yingxia Yang, Minjie Lu, Xuechun Guan, Shihua Zhao, Liling Long

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引用次数: 0

Abstract

Purpose: To evaluate the left atrial (LA) function in participants with apical hypertrophic cardiomyopathy (AHCM) by cardiovascular magnetic resonance feature tracking (CMR-FT).

Materials and methods: Thirty typical AHCM (TAHCM) patients, 23 subclinical AHCM (SAHCM) patients and 32 normal healthy volunteers who underwent CMR exam were retrospectively analyzed. LA reservoir, conduit, and contractile function were quantified by volumetric and CMR-FT derived strain and strain rate (SR) parameters from 2-chamber and 4-chamber cine imaging.

Results: Compared with healthy participants, both TAHCM and SAHCM patients had impaired LA reservoir function (total strain [%]: TAHCM 31.3±12.2, SAHCM 31.8±12.3, controls 40.4±10.7, P <0.01; total SR [/s]: TAHCM 1.1±0.4, SAHCM 1.1±0.5, controls 1.4 ± 0.4, P <0.01) and conduit function (passive strain [%]: TAHCM 14.4±7.6, SAHCM 16.4±8.8, controls 23.3±8.1, P <0.01; passive SR [/s]: TAHCM -0.5±0.3, SAHCM -0.6±0.3, controls -1.0±0.4, P <0.01). Regarding contraction function, although TAHCM and SAHCM patients had preserved active emptying fraction and strain (all P >0.05), patients with TAHCM had the lowest active SR value among the 3 groups ( P= 0.03). LA reservoir and conduit strain were both significantly associated with left ventricular mass index and maximal wall thickness (all P <0.05). A moderate correlation between LA passive SR and left ventricular cardiac index ( P <0.01).

Conclusions: The LA reservoir and conduit function are predominately impaired and appeared in both SAHCM and TAHCM patients.

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尖端肥厚型心肌病的左心房功能障碍：心血管磁共振特征追踪评估。

目的：通过心血管磁共振特征追踪（CMR-FT）评估心尖肥厚型心肌病（AHCM）患者的左心房（LA）功能：回顾性分析30名典型AHCM（TAHCM）患者、23名亚临床AHCM（SAHCM）患者和32名接受CMR检查的正常健康志愿者。通过两腔和四腔电影成像的容积参数和 CMR-FT 导出的应变和应变率（SR）参数对 LA 储库、导管和收缩功能进行量化：与健康参试者相比，TAHCM 和 SAHCM 患者的 LA 储库功能均受损（总应变[%]：TAHCM 31.3±12 mmHg，SAHCM 31.3±12 mmHg）：总应变[%]：TAHCM 31.3±12.2，SAHCM 31.8±12.3，对照组 40.4±10.7，P 0.05），TAHCM 患者的活动 SR 值在三组患者中最低（P= 0.03）。LA 储库和导水管应变均与左心室质量指数和最大室壁厚度显著相关（均为 P 结论：LA 储库和导水管应变与左心室质量指数和最大室壁厚度显著相关（均为 PSAHCM和TAHCM患者的LA储腔和导水管功能主要受损。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Thoracic Imaging 医学-核医学

CiteScore

7.10

自引率

9.10%

发文量

审稿时长

6-12 weeks

期刊介绍： Journal of Thoracic Imaging (JTI) provides authoritative information on all aspects of the use of imaging techniques in the diagnosis of cardiac and pulmonary diseases. Original articles and analytical reviews published in this timely journal provide the very latest thinking of leading experts concerning the use of chest radiography, computed tomography, magnetic resonance imaging, positron emission tomography, ultrasound, and all other promising imaging techniques in cardiopulmonary radiology. Official Journal of the Society of Thoracic Radiology: Japanese Society of Thoracic Radiology Korean Society of Thoracic Radiology European Society of Thoracic Imaging.

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