Exposure to particulate matter: a brief review with a focus on cardiovascular effects, children, and research conducted in Turkey.

IF 1.7 4区医学 Q3 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH

Arhiv Za Higijenu Rada I Toksikologiju-Archives of Industrial Hygiene and Toxicology Pub Date : 2021-12-30 DOI:10.2478/aiht-2021-72-3563

Aylin Elkama, Ayça Aktaş Şüküroğlu, Gonca Çakmak

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引用次数: 0

Abstract

Exposure to environmental particulate matter (PM), outdoor air pollution in particular, has long been associated with adverse health effects. Today, PM has widely been accepted as a systemic toxicant showing adverse effects beyond the lungs. There are numerous studies, from those in vitro to epidemiological ones, suggesting various direct and indirect PM toxicity mechanisms associated with cardiovascular risks, including inflammatory responses, oxidative stress, changes in blood pressure, autonomic regulation of heart rate, suppression of endothelium-dependent vasodilation, thrombogenesis, myocardial infarction, and fibrinolysis. In addition to these and other health risks, considerations about air quality standards should include individual differences, lifestyle, and vulnerable populations such as children. Urban air pollution has been a major environmental issue for Turkey, and this review will also address current situation, research, and measures taken in our country.

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接触微粒物质：简要回顾，重点关注对心血管的影响、儿童以及在土耳其开展的研究。

接触环境颗粒物（PM），尤其是室外空气污染，长期以来一直与不良健康影响有关。如今，人们普遍认为可吸入颗粒物是一种全身性毒物，其不良影响超出了肺部。从体外研究到流行病学研究，有大量研究表明，可吸入颗粒物的各种直接和间接毒性机制与心血管风险有关，包括炎症反应、氧化应激、血压变化、心率的自主调节、抑制内皮依赖性血管扩张、血栓形成、心肌梗塞和纤维蛋白溶解。除了这些和其他健康风险外，有关空气质量标准的考虑因素还应包括个体差异、生活方式和儿童等弱势群体。城市空气污染一直是土耳其的一个主要环境问题，本综述也将讨论我国的现状、研究和采取的措施。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Arhiv Za Higijenu Rada I Toksikologiju-Archives of Industrial Hygiene and Toxicology PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH-TOXICOLOGY

CiteScore

3.50

自引率

4.80%

发文量

审稿时长

6-12 weeks

期刊介绍： Archives of Industrial Hygiene and Toxicology (abbr. Arh Hig Rada Toksikol) is a peer-reviewed biomedical scientific quarterly that publishes contributions relevant to all aspects of environmental and occupational health and toxicology.