Exploring the Potential of Stem Cell-Based Therapy for Aesthetic and Plastic Surgery

IF 17.2 1区工程技术 Q1 ENGINEERING, BIOMEDICAL

IEEE Reviews in Biomedical Engineering Pub Date : 2021-12-14 DOI:10.1109/RBME.2021.3134994

Dang-Khoa Tran;Thuy Nguyen Thi Phuong;Nhat-Le Bui;Vijai Singh;Qi Hao Looi;Benson Koh;Ungku Mohd Shahrin B Mohd Zaman;Jhi Biau Foo;Chia-Ching Wu;Pau Loke Show;Dinh-Toi Chu

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引用次数: 6

Abstract

Over the last decade, stem cell-associated therapies are widely used because of their potential in self-renewable and multipotent differentiation ability. Stem cells have become more attractive for aesthetic uses and plastic surgery, including scar reduction, breast augmentation, facial contouring, hand rejuvenation, and anti-aging. The current preclinical and clinical studies of stem cells on aesthetic uses also showed promising outcomes. Adipose-derived stem cells are commonly used for fat grafting that demonstrated scar improvement, anti-aging, skin rejuvenation properties, etc. While stem cell-based products have yet to receive approval from the FDA for aesthetic medicine and plastic surgery. Moving forward, the review on the efficacy and potential of stem cell-based therapy for aesthetic and plastic surgery is limited. In the present review, we discuss the current status and recent advances of using stem cells for aesthetic and plastic surgery. The potential of cell-free therapy and tissue engineering in this field is also highlighted. The clinical applications, advantages, and limitations are also discussed. This review also provides further works that need to be investigated to widely apply stem cells in the clinic, especially in aesthetic and plastic contexts.

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探索以干细胞为基础的美容整形治疗潜力

在过去的十年里，干细胞相关疗法因其具有自我再生和多能分化能力的潜力而被广泛使用。干细胞在美容和整形手术方面变得更有吸引力，包括减少疤痕、隆胸、面部轮廓、手部年轻化和抗衰老。目前对干细胞美容用途的临床前和临床研究也显示出了有希望的结果。脂肪来源的干细胞通常用于脂肪移植，具有改善疤痕、抗衰老、皮肤再生等特性。而基于干细胞的产品尚未获得美国食品药品监督管理局的美容医学和整形外科批准。展望未来，对基于干细胞的美容整形治疗的疗效和潜力的综述是有限的。在这篇综述中，我们讨论了利用干细胞进行美容和整形手术的现状和最新进展。无细胞治疗和组织工程在该领域的潜力也得到了强调。还讨论了其临床应用、优点和局限性。这篇综述还提供了需要研究的进一步工作，以在临床上广泛应用干细胞，特别是在美容和整形方面。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

IEEE Reviews in Biomedical Engineering Engineering-Biomedical Engineering

CiteScore

31.70

自引率

0.60%

发文量

期刊介绍： IEEE Reviews in Biomedical Engineering (RBME) serves as a platform to review the state-of-the-art and trends in the interdisciplinary field of biomedical engineering, which encompasses engineering, life sciences, and medicine. The journal aims to consolidate research and reviews for members of all IEEE societies interested in biomedical engineering. Recognizing the demand for comprehensive reviews among authors of various IEEE journals, RBME addresses this need by receiving, reviewing, and publishing scholarly works under one umbrella. It covers a broad spectrum, from historical to modern developments in biomedical engineering and the integration of technologies from various IEEE societies into the life sciences and medicine.