Surgical treatment of non-cystic fibrosis bronchiectasis in children and adolescents: A review

IF 5.4 3区 材料科学 Q2 CHEMISTRY, PHYSICAL
Helena Teresinha Mocelin , Gilberto Bueno Fischer , Júlia Danezi Piccini , Renata Baú , Cristiano Feijó Andrade , Janice Luisa Lukrafka
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引用次数: 0

Abstract

Objective

To discuss surgery for non-cystic fibrosis [CF] bronchiectasis in children and adolescents.

Sources

Non-systematic review including articles in English, mainly from the last 5 years.

Summary of findings

In this review, we present that in low- and middle-income countries [LMIC] clinical treatment fails in around 20% of cases due to low socioeconomic status and poor adherence. This causes the disease to progress and require surgery. We emphasize that the indications for surgery are not well defined and must be considered on an individual basis. The surgical treatment of bronchiectasis in children may be indicated in selected cases; especially in localized disease with frequent exacerbations despite an optimized clinical approach. Surgery can improve quality of life [QoL] and reduce exacerbations. It has few postoperative complications and low morbidity and mortality. Finally, we propose an algorithm for managing bronchiectasis, which takes into account LMIC settings with limited resources.

Conclusion

We conclude that in LMICs, surgery is a treatment strategy for selected children/adolescents with bronchiectasis.

儿童和青少年非囊性纤维化支气管扩张症的手术治疗:综述
目的探讨儿童和青少年非囊性纤维化支气管扩张症的手术治疗。资料来源非系统综述,包括主要来自过去5年的英文文章。研究结果摘要在这篇综述中,我们发现,在中低收入国家,约20%的病例由于社会经济地位低和依从性差而导致临床治疗失败。这会导致疾病进展,需要手术治疗。我们强调,手术适应症没有很好的定义,必须根据个人情况进行考虑。儿童支气管扩张症的外科治疗可能在选定的病例中适用;尤其是在尽管采用了优化的临床方法但仍经常恶化的局部疾病中。手术可以提高生活质量,减少病情恶化。术后并发症少,发病率和死亡率低。最后,我们提出了一种管理支气管扩张症的算法,该算法考虑了资源有限的LMIC设置。结论我们得出的结论是,在LMIC中,手术是选择儿童/青少年支气管扩张症的治疗策略。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
ACS Applied Energy Materials
ACS Applied Energy Materials Materials Science-Materials Chemistry
CiteScore
10.30
自引率
6.20%
发文量
1368
期刊介绍: ACS Applied Energy Materials is an interdisciplinary journal publishing original research covering all aspects of materials, engineering, chemistry, physics and biology relevant to energy conversion and storage. The journal is devoted to reports of new and original experimental and theoretical research of an applied nature that integrate knowledge in the areas of materials, engineering, physics, bioscience, and chemistry into important energy applications.
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