The role of pharmaceutical side-effects in depression among immigrants.

IF 2.6 3区 医学 Q1 ETHNIC STUDIES
Duy Do, Jason Schnittker
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引用次数: 0

Abstract

Objectives: This study explores the role of pharmaceuticals with depression or suicidality as a side-effect in explaining the immigrant depression paradox. Immigrants generally report less depression than their native-born peers, despite the socio environments that are less conducive to well-being. This immigrant advantage in mental health tends to recede with time in the US and more acculturation. To date, an explanation for this pattern has remained elusive, partly because acculturation is also associated with many desirable outcomes, suggesting less depression with more acculturation.

Design: Data came from seven two-year waves (2005-2006 to 2017-2018) of the National Health and Nutrition Examination Survey (NHANES). Depression was measured using the Patient Health Questionnaire (PHQ-9). Linear and logistic regressions were used to estimate the immigrant differences in depression, while controlling for sociodemographic characteristics, healthcare access, health conditions, and the use of medications with depression or suicidality as a side-effect.

Results: 30.3% and 22.7% of US-born adults used at least one medication with depression or suicidality as a side-effect, compared to 16.4% and 9.2% of foreign-born adults. Access to healthcare improved with time in the US and with acculturation, and both of these factors were also positively associated with the use of medications with depression or suicidality as a side-effect. The magnitude of the mediation associated with medication side-effects was significant, in many cases sufficient to eliminate the relationship between acculturation - whether expressed in terms of time in the US, English-language use, or nativity - and depression.

Conclusion: Exposure to medications with depression or suicidality as a side-effect helped explain part of the relative mental health advantage of foreign-born residents, as well as the diminishing advantage associated with time in the US and with acculturation.

药物副作用在移民抑郁中的作用。
目的:本研究探讨药物与抑郁或自杀的副作用在解释移民抑郁悖论中的作用。尽管移民的社会环境不太有利于幸福,但移民总体上比本土出生的同龄人更少患抑郁症。移民在心理健康方面的优势往往会随着在美国的时间和更多的文化适应而消退。迄今为止,对这种模式的解释仍然难以捉摸,部分原因是文化适应也与许多理想的结果有关,这表明文化适应程度越高,抑郁症越少。设计:数据来自国家健康与营养检查调查(NHANES)的七次为期两年的浪潮(2005-2006年至2017-2018年)。使用患者健康问卷(PHQ-9)测量抑郁症。使用线性和逻辑回归来估计移民在抑郁症方面的差异,同时控制社会人口统计学特征、医疗保健可及性、健康状况以及使用导致抑郁症或自杀的药物作为副作用。结果:30.3%和22.7%在美国出生的成年人至少使用过一种药物,其副作用为抑郁或自杀,而在外国出生的成年人中这一比例分别为16.4%和9.2%。在美国,随着时间的推移和文化的适应,获得医疗保健的机会有所改善,这两个因素也与使用有抑郁或自杀副作用的药物呈正相关。与药物副作用相关的调解的重要性是显著的,在许多情况下足以消除文化适应之间的关系-无论是在美国的时间,英语使用还是出生-和抑郁症。结论:暴露于具有抑郁或自杀副作用的药物有助于部分解释外国出生居民的相对心理健康优势,以及随着在美国的时间和文化适应而减少的优势。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Ethnicity & Health
Ethnicity & Health 医学-公共卫生、环境卫生与职业卫生
CiteScore
6.50
自引率
0.00%
发文量
42
审稿时长
>12 weeks
期刊介绍: Ethnicity & Health is an international academic journal designed to meet the world-wide interest in the health of ethnic groups. It embraces original papers from the full range of disciplines concerned with investigating the relationship between ’ethnicity’ and ’health’ (including medicine and nursing, public health, epidemiology, social sciences, population sciences, and statistics). The journal also covers issues of culture, religion, gender, class, migration, lifestyle and racism, in so far as they relate to health and its anthropological and social aspects.
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