The role of the dentist and the orthodontist in early diagnosis of Gorlin-Goltz syndrome: a cephalometric and photometric study.

IF 2.2 2区 医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE
M C Meazzini, L P Demonte, L Conti, L Autelitano, N Cohen, F Mazzoleni
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引用次数: 0

Abstract

Aim: The aim of this study was to analyse the facial characteristics and the craniofacial morphology in GGS patients in order to enable an early diagnosis.

Background: Gorlin-Goltz syndrome (GGS) is a autosomic dominant disease, characterised by basal cell carcinoma, palmar/plantar pits, maxillary and mandibular keratocysts and dental abnormalities.

Methods: Nine out of a sample of 24 GGS patients had complete cephalometric and photographic records at an average age of 8.7 years. Cephalometric and photometric analysis were carried out with standard analyses and compared with healthy patients matched for sex and age.

Conclusion: Early diagnosis of GGS based on clinical features could be useful to identify the presence of keratocysts through x-ray examination proceeding with surgical removal at an early stage, limiting space occupying damages.

牙医和正畸医师在Gorlin-Goltz综合征早期诊断中的作用:一项颅面测量和光度研究。
目的:本研究的目的是分析GGS患者的面部特征和颅面形态,以便早期诊断。背景:Gorlin-Goltz综合征(GGS)是一种常染色体显性疾病,以基底细胞癌、掌/足底窝、上颌和下颌角化囊肿和牙齿异常为特征。方法:24例GGS患者中有9例有完整的头颅测量和摄影记录,平均年龄8.7岁。头颅测量和光度分析采用标准分析,并与性别和年龄相匹配的健康患者进行比较。结论:根据临床特征对GGS进行早期诊断,通过x线检查发现角化囊肿的存在,及早手术切除,限制占位性损害。
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来源期刊
European journal of paediatric dentistry
European journal of paediatric dentistry DENTISTRY, ORAL SURGERY & MEDICINE-PEDIATRICS
CiteScore
4.60
自引率
19.40%
发文量
43
审稿时长
6-12 weeks
期刊介绍: The aim and scope of the European Journal of Paediatric Dentistry is to promote research in all aspects of dentistry related to children, including interceptive orthodontics and studies on children and young adults with special needs.
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