Prevalence of poor nutrition status in multiple sclerosis patients assessed by different diagnostic tools.

IF 1.4 4区生物学 Q4 BIOCHEMISTRY & MOLECULAR BIOLOGY

Acta biochimica Polonica Pub Date : 2023-05-31 DOI:10.18388/abp.2020_6578

Natalia Mogiłko, Sylwia Malgorzewicz

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Abstract

Patients with multiple sclerosis (MS) present a spectrum of nutritional disorders from obesity to malnutrition. The purpose of this study was an assessment of the nutritional status of MS patients by NRS-2002 and GLIM criteria.

Methods: 147 patients were included in the study. The nutritional status was assessed by NRS 2002, GLIM, and body composition analysis. The routine biochemical parameters were measured.

Results: Deterioration of the nutritional status was observed in 87.8% of patients. GLIM criteria indicated that 20% of patients were malnourished and 80% were at risk. The percentage of patients with excess body mass was 46.8%, and of underweight patients was 6.6%. The risk of malnutrition was positively associated with low content of adipose tissue (R=-0.24; p=0.00), low BMI (R=-0.22; p=0.00), and higher weight loss in the last 6 months (R=0.47; p=0.00). Additionally, a significant (p<0.05) correlation between malnutrition state and s-albumin (R=-0.2) and CRP (R=0.23) was observed.

Conclusion: Overweight and obesity concerned a large proportion of the studied group of MS patients, but this does not exclude the risk of malnutrition. Dietary care and regular outpatient nutritional status assessment should be provided throughout the disease.

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不同诊断工具评估多发性硬化症患者营养不良状况的患病率。

多发性硬化症(MS)患者表现出从肥胖到营养不良的一系列营养失调。本研究的目的是通过NRS-2002和GLIM标准评估多发性硬化症患者的营养状况。方法:147例患者纳入研究。营养状况通过NRS 2002、GLIM和身体成分分析进行评估。测定常规生化指标。结果:87.8%的患者出现营养状况恶化。GLIM标准显示20%的患者营养不良，80%处于危险中。体重超标患者占46.8%，体重过轻患者占6.6%。营养不良的风险与脂肪组织含量低呈正相关(R=-0.24;p=0.00)，低BMI (R=-0.22;p=0.00)，且最近6个月体重下降幅度较大(R=0.47;p = 0.00)。结论:超重和肥胖在研究组MS患者中占很大比例，但这并不排除营养不良的风险。在整个疾病期间应提供饮食护理和定期门诊营养状况评估。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Acta biochimica Polonica 生物-生化与分子生物学

CiteScore

2.40

自引率

0.00%

发文量

审稿时长

4-8 weeks

期刊介绍： Acta Biochimica Polonica is a journal covering enzymology and metabolism, membranes and bioenergetics, gene structure and expression, protein, nucleic acid and carbohydrate structure and metabolism.