Vaccination and treatment options for SARS-CoV2 infection affecting lactation and breastfeeding

IF 2.9 3区 医学 Q1 PEDIATRICS
Melissa J. Chen , Ritu Cheema , Adrienne Hoyt-Austin , Alicia Agnoli , Kara Kuhn-Riordon , Laura R. Kair
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引用次数: 4

Abstract

The COVID-19 pandemic has posed considerable challenges to the health of lactating individuals. Vaccination remains one of the most important strategies for prevention of moderate to severe COVID-19 infection and is associated with protective benefits for lactating individuals and their breastfed infants with overall mild side effects. The current recommendations for COVID-19 treatment in lactating individuals includes remdesivir and dexamethasone for hospitalized patients and Paxlovid® (nirmatrelavir + ritonavir) as outpatient treatment in those with mild disease. As the pandemic continues to evolve with new COVID-19 variants, alternative therapeutic options are potentially needed, and it is critical to include lactating individuals in research to evaluate the safety and efficacy of COVID-19 treatment options in this population.

Abstract Image

影响哺乳和母乳喂养的严重急性呼吸系统综合征冠状病毒感染的疫苗接种和治疗方案
新冠肺炎大流行对哺乳期个体的健康构成了相当大的挑战。接种疫苗仍然是预防中重度新冠肺炎感染的最重要策略之一,对哺乳期个体及其总体副作用较轻的母乳喂养婴儿具有保护作用。目前对哺乳期患者新冠肺炎治疗的建议包括对住院患者使用瑞德西韦和地塞米松,对轻症患者使用奈玛特韦片/利托那韦片组合包装®(nirmatrevir+利托那韦)作为门诊治疗。随着新的新冠肺炎变种的不断发展,可能需要替代治疗方案,将哺乳期个体纳入研究以评估新冠肺炎治疗方案在该人群中的安全性和有效性至关重要。
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来源期刊
CiteScore
6.40
自引率
3.30%
发文量
49
审稿时长
6-12 weeks
期刊介绍: Seminars in Fetal & Neonatal Medicine (formerly Seminars in Neonatology) is a bi-monthly journal which publishes topic-based issues, including current ''Hot Topics'' on the latest advances in fetal and neonatal medicine. The Journal is of interest to obstetricians and maternal-fetal medicine specialists. The Journal commissions review-based content covering current clinical opinion on the care and treatment of the pregnant patient and the neonate and draws on the necessary specialist knowledge, including that of the pediatric pulmonologist, the pediatric infectious disease specialist, the surgeon, as well as the general pediatrician and obstetrician. Each topic-based issue is edited by an authority in their field and contains 8-10 articles. Seminars in Fetal & Neonatal Medicine provides: • Coverage of major developments in neonatal care; • Value to practising neonatologists, consultant and trainee pediatricians, obstetricians, midwives and fetal medicine specialists wishing to extend their knowledge in this field; • Up-to-date information in an attractive and relevant format.
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