Comprehensive and heart-cutting multidimensional liquid chromatography–mass spectrometry and its applications in food analysis

IF 6.9 2区化学 Q1 SPECTROSCOPY

Mass Spectrometry Reviews Pub Date : 2023-04-13 DOI:10.1002/mas.21845

Irene Caño-Carrillo, Bienvenida Gilbert-López, Lidia Montero, Ana B. Martínez-Piernas, Juan F. García-Reyes, Antonio Molina-Díaz

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Abstract

In food analysis, conventional one-dimensional liquid chromatography methods sometimes lack sufficient separation power due to the complexity and heterogeneity of the analyzed matrices. Therefore, the use of two-dimensional liquid chromatography (2D-LC) turns out to be a powerful tool to consider, especially when coupled to mass spectrometry (MS). This review presents the most remarkable 2D-LC–MS food applications reported in the last 10 years, including a critical discussion of the multiple approaches, modulation strategies as well as the importance of the optimization of the different analytical aspects that will condition the 2D-LC–MS performance. The presence of contaminants in food (food safety), the food quality, and authenticity or the relationship between the beneficial effects of food and human health are some of the fields in which most of the 2D-LC–MS applications are mainly focused. Both heart-cutting and comprehensive applications are described and discussed in this review, highlighting the potential of 2D-LC–MS for the analysis of such complex samples.

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多维液相色谱-质谱联用技术及其在食品分析中的应用。

在食品分析中，由于分析基质的复杂性和异质性，传统的一维液相色谱法有时会缺乏足够的分离能力。因此，使用二维液相色谱法（2D-LC）成为一种值得考虑的强大工具，尤其是在与质谱联用时。本综述介绍了过去 10 年中报道的最杰出的二维液相色谱-质谱食品应用，包括对多种方法、调节策略以及优化不同分析方面的重要性的重要讨论，这些方面将对二维液相色谱-质谱的性能产生影响。食品中是否存在污染物（食品安全）、食品质量和真实性或食品的有益作用与人体健康之间的关系是大多数 2D-LC-MS 应用主要关注的一些领域。本综述介绍并讨论了二维液相色谱-质谱（2D-LC-MS）在此类复杂样品分析中的应用潜力。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Mass Spectrometry Reviews 物理-光谱学

CiteScore

16.30

自引率

3.00%

发文量

期刊介绍： The aim of the journal Mass Spectrometry Reviews is to publish well-written reviews in selected topics in the various sub-fields of mass spectrometry as a means to summarize the research that has been performed in that area, to focus attention of other researchers, to critically review the published material, and to stimulate further research in that area. The scope of the published reviews include, but are not limited to topics, such as theoretical treatments, instrumental design, ionization methods, analyzers, detectors, application to the qualitative and quantitative analysis of various compounds or elements, basic ion chemistry and structure studies, ion energetic studies, and studies on biomolecules, polymers, etc.