Mild COVID-19 has no detrimental effect on semen quality.

IF 2.4 3区医学 Q2 ANDROLOGY

Basic and Clinical Andrology Pub Date : 2023-06-15 DOI:10.1186/s12610-023-00190-2

Philippos Edimiris, Cornelius Doehmen, Lisa Müller, Marcel Andrée, Dunja Maria Baston-Buest, Sebastian Buest, Ortwin Adams, Jan-Steffen Krüssel, Alexandra Petra Bielfeld

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引用次数: 0

Abstract

Background: As of today, the effect of coronavirus disease 2019 (COVID-19) on male fertility remains unclear. Studies published so far have partly contradictory results, likely due to very small sample sizes and heterogeneous populations. To gain a deeper understanding of the impact of COVID-19 on male fertility, we performed a prospective case-control study, in which we examined the ejaculate of 37 subjects, including 25 subjects in the acute phase of mild COVID-19 and 12 subjects who did not suffer from COVID-19. Determination of semen parameters, severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2) qPCR, and infectivity analysis were performed in the acute phase of the disease and in series.

Results: Semen parameter values did not differ significantly between subjects with mild COVID-19 and the control group. The serial examination of semen parameters revealed no significant changes between 4, 18, and 82 days after the onset of symptoms. SARS-CoV-2 RNA or infectious particles could not be detected in any ejaculate.

Conclusion: Mild COVID-19 seems to have no detrimental effect on semen parameter values.

Abstract Image

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轻度COVID-19对精液质量没有不利影响。

背景:截至目前，2019冠状病毒病(COVID-19)对男性生育能力的影响尚不清楚。到目前为止发表的研究结果在一定程度上是相互矛盾的，这可能是由于样本量很小，人群异质性很大。为了更深入地了解COVID-19对男性生育能力的影响，我们进行了一项前瞻性病例对照研究，在该研究中，我们检查了37名受试者的射精，其中25名受试者处于轻度COVID-19急性期，12名受试者未患COVID-19。在疾病急性期和系列中进行精液参数测定、严重急性呼吸综合征冠状病毒2型(SARS-CoV-2) qPCR和传染性分析。结果:轻症患者精液各项指标与对照组无显著差异。精液参数的系列检查显示，在症状出现后4、18和82天没有明显变化。所有射精均未检出SARS-CoV-2 RNA或感染性颗粒。结论:轻度COVID-19似乎对精液参数值无不利影响。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Basic and Clinical Andrology Medicine-Urology

CiteScore

3.50

自引率

0.00%

发文量

审稿时长

22 weeks

期刊介绍： Basic and Clinical Andrology is an open access journal in the domain of andrology covering all aspects of male reproductive and sexual health in both human and animal models. The journal aims to bring to light the various clinical advancements and research developments in andrology from the international community.