Urinary Tract Infection and Associated Factors among Pregnant Women Receiving Antenatal Care at a Primary Health Care Facility in the Northern Region of Ghana.

IF 2.8 Q3 MICROBIOLOGY
Ezekiel K Vicar, Samuel E K Acquah, Williams Wallana, Eugene D Kuugbee, Emmanuel K Osbutey, Abigail Aidoo, Emmanuel Acheampong, Gloria Ivy Mensah
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引用次数: 2

Abstract

Urinary tract infection (UTI) is frequently encountered during pregnancy and is associated with adverse maternal, fetal, and neonatal effects. However, very little information is available on the prevalence of UTI among pregnant women in the northern part of Ghana, a region with a high birth rate. This study employed a cross-sectional analysis of the prevalence, antimicrobial profile, and risk factors associated with UTI in 560 pregnant women attending primary care for antenatal check-ups. Sociodemographic obstetrical history and personal hygiene information were obtained using a well-structured questionnaire. Afterward, clean catch mid-stream urine samples were collected from all participants and subjected to routine microscopy examination and culture. Of 560 pregnant women, 223 cases (39.8%) were positive for UTI. There was a statistically significant association between sociodemographic, obstetric, and personal hygiene variables and UTI (p < 0.0001). Escherichia coli (27.8%) was the commonest bacterial isolate followed by CoNS (13.5%) and Proteus species (12.6%). These isolates exhibited greater resistance to ampicillin (70.1-97.3%) and cotrimoxazole (48.1-89.7%) but were fairly susceptible to gentamycin and ciprofloxacin. Gram-negative resistance to meropenem was up to 25.0%, and Gram positives resistance to cefoxitin and vancomycin was up to 33.3% and 71.4% respectively. The current findings extend our knowledge of the high frequency of UTIs and associated risk factors in pregnant women with E. Coli being the predominant and usual isolate. Variation existed in the resistance pattern of isolates to various drugs, underscoring the need to perform urine culture and susceptibility before treatment.

Abstract Image

Abstract Image

在加纳北部地区初级卫生保健机构接受产前护理的孕妇中的尿路感染及其相关因素。
尿路感染(UTI)是怀孕期间经常遇到的,并与母体,胎儿和新生儿的不良影响有关。然而,关于加纳北部孕妇中尿路感染流行情况的信息很少,而该地区的出生率很高。本研究对560名接受初级保健产前检查的孕妇的尿路感染流行率、抗菌素特征和相关危险因素进行了横断面分析。使用结构良好的问卷获得社会人口统计学、产科史和个人卫生信息。随后,从所有参与者收集干净的中游尿液样本,并进行常规显微镜检查和培养。560例孕妇中,223例(39.8%)尿路感染阳性。社会人口学、产科和个人卫生变量与尿路感染之间存在统计学上显著的关联(p < 0.0001)。最常见的细菌分离物为大肠杆菌(27.8%),其次为con(13.5%)和变形杆菌(12.6%)。这些分离株对氨苄西林(70.1 ~ 97.3%)和复方新诺明(48.1 ~ 89.7%)的耐药性较高,但对庆大霉素和环丙沙星相当敏感。对美罗培南革兰氏阴性耐药率高达25.0%,对头孢西丁和万古霉素革兰氏阳性耐药率分别高达33.3%和71.4%。目前的研究结果扩展了我们对孕妇中尿路感染的高频率和相关危险因素的认识,大肠杆菌是主要和常见的分离物。分离株对不同药物的耐药模式存在差异,强调需要在治疗前进行尿液培养和药敏。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
7.90
自引率
0.00%
发文量
57
审稿时长
13 weeks
期刊介绍: International Journal of Microbiology is a peer-reviewed, Open Access journal that publishes original research articles, review articles, and clinical studies on microorganisms and their interaction with hosts and the environment. The journal covers all microbes, including bacteria, fungi, viruses, archaea, and protozoa. Basic science will be considered, as well as medical and applied research.
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