Systemic Immune-Inflammation Index in Diabetic Foot Infections and Osteomyelitis.

IF 2.2 4区医学 Q3 DERMATOLOGY

International Journal of Lower Extremity Wounds Pub Date : 2025-12-01 Epub Date: 2023-06-01 DOI:10.1177/15347346231179280

Javier Aragón-Sánchez, Gerardo Víquez-Molina, María Eugenia López-Valverde, José María Rojas-Bonilla

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Abstract

The systemic immune-inflammation index (SII) was significantly higher in patients with severe infections, those with necrosis, and in those requiring admission, postoperative antibiotics, and any amputation. However, SII was significantly lower in patients with osteomyelitis compared to those with soft tissue infections. The correlation coefficients (rho) between SII and other inflammatory markers were as follows: WBC (Moderate correlation, 0.64, P < .001), ESR (Weak correlation, 0.34, P < .001), and CRP (Moderate correlation, 0.56, P < .001). The correlation coefficient (rho) between SII and the number of days admitted was moderate, 0.42 (P < .001). Based on a previous experience, SII may be an additional marker to diagnose osteomyelitis in the feet of patients with diabetes. Now, we need further research including SII, a low-cost and easy-to-measure index, in well-designed controlled studies to definitively clarify its role.

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糖尿病足感染和骨髓炎的全身免疫炎症指数。

严重感染患者、坏死患者以及需要住院、术后使用抗生素和截肢的患者的全身免疫炎症指数（SII）明显较高。然而，骨髓炎患者的SII明显低于软组织感染患者。SII与其他炎症指标的相关系数（rho）如下：WBC(中度相关，0.64,P P P P P

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来源期刊

International Journal of Lower Extremity Wounds DERMATOLOGY-SURGERY

CiteScore

4.60

自引率

17.60%

发文量

审稿时长

>12 weeks

期刊介绍： The International Journal of Lower Extremity Wounds (IJLEW) is a quarterly, peer-reviewed journal publishing original research, reviews of evidence-based diagnostic techniques and methods, disease and patient management, and surgical and medical therapeutics for lower extremity wounds such as burns, stomas, ulcers, fistulas, and traumatic wounds. IJLEW also offers evaluations of assessment and monitoring tools, dressings, gels, cleansers, pressure management, footwear/orthotics, casting, and bioengineered skin. This journal is a member of the Committee on Publication Ethics (COPE).