On a simple estimation of the proportional odds model under right truncation.

IF 16.4 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Accounts of Chemical Research Pub Date : 2023-07-01 DOI:10.1007/s10985-022-09584-2

Peng Liu, Kwun Chuen Gary Chan, Ying Qing Chen

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Abstract

Retrospective sampling can be useful in epidemiological research for its convenience to explore an etiological association. One particular retrospective sampling is that disease outcomes of the time-to-event type are collected subject to right truncation, along with other covariates of interest. For regression analysis of the right-truncated time-to-event data, the so-called proportional reverse-time hazards model has been proposed, but the interpretation of its regression parameters tends to be cumbersome, which has greatly hampered its application in practice. In this paper, we instead consider the proportional odds model, an appealing alternative to the popular proportional hazards model. Under the proportional odds model, there is an embedded relationship between the reverse-time hazard function and the usual hazard function. Building on this relationship, we provide a simple procedure to estimate the regression parameters in the proportional odds model for the right truncated data. Weighted estimations are also studied.

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右截断下比例赔率模型的简单估计。

回顾性抽样在流行病学研究中是有用的，因为它便于探索病原学关联。一种特殊的回顾性抽样是，对事件发生时间类型的疾病结果以及其他感兴趣的协变量进行右截断。对于右截断时间-事件数据的回归分析，提出了所谓的比例逆时风险模型，但其回归参数的解释往往比较繁琐，极大地阻碍了其在实际中的应用。在本文中，我们转而考虑比例赔率模型，这是流行的比例风险模型的一个有吸引力的替代方案。在比例赔率模型下，逆时风险函数与通常风险函数之间存在嵌入关系。在这种关系的基础上，我们提供了一个简单的过程来估计右侧截断数据的比例赔率模型中的回归参数。对加权估计也进行了研究。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Accounts of Chemical Research 化学-化学综合

CiteScore

31.40

自引率

1.10%

发文量

312

审稿时长

2 months

期刊介绍： Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.