Breaking the unbreakable: A paediatric case of dolutegravir resistance from KwaZulu-Natal.

IF 1.6 4区医学 Q4 INFECTIOUS DISEASES

Southern African Journal of Hiv Medicine Pub Date : 2023-01-01 DOI:10.4102/sajhivmed.v24i1.1458

Sibongiseni Malinga, Aabida Khan, Moherndran Archary

引用次数: 3

Abstract

We report a case of dolutegravir resistance in KwaZulu-Natal in a 13-year-old male two years after starting dolutegravir. Resistance most likely developed due to poor adherence as a result of psychosocial issues. This case highlights the importance of the role of the family unit in impacting adherence and close monitoring of treatment-experienced patients with virologic failure following switching to dolutegravir-based regimens.

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打破坚不可摧:夸祖鲁-纳塔尔省一例小儿多替格拉耐药病例。

我们报告了一例在夸祖鲁-纳塔尔省的一名13岁男性在开始使用多鲁特韦两年后出现多鲁特韦耐药性的病例。耐药性很可能是由于社会心理问题导致的依从性差而产生的。该病例强调了家庭单位在影响依从性和密切监测治疗经验丰富的病毒学失败患者在切换到以多替尼韦为基础的方案后的重要性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Southern African Journal of Hiv Medicine 医学-病毒学

CiteScore

2.80

自引率

11.80%

发文量

审稿时长

>12 weeks

期刊介绍： The Southern African Journal of HIV Medicine is focused on HIV/AIDS treatment, prevention and related topics relevant to clinical and public health practice. The purpose of the journal is to disseminate original research results and to support high-level learning related to HIV Medicine. It publishes original research articles, editorials, case reports/case series, reviews of state-of-the-art clinical practice, and correspondence.