Preoperative Opioid Therapy Correlated With Increased Rate of Complications in Foot and Ankle Surgery.

IF 2.1
Foot & ankle specialist Pub Date : 2025-08-01 Epub Date: 2023-06-11 DOI:10.1177/19386400231177581
Kevin Shrake, William Newton, Caroline Hoch, Annemarie Galasso, Daniel J Scott, Christopher E Gross
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Abstract

BackgroundThe purpose of this study is to determine whether patients with a history of preoperative opioid use will have an increased likelihood of postoperative opioid use and complications after undergoing forefoot, hindfoot, or ankle surgery.MethodsA retrospective review was conducted on forefoot, hindfoot, and ankle surgeries between 2015 and 2020 with a single fellowship-trained orthopaedic foot and ankle surgeon at an academic medical center. A total of 326 patients (356 feet) were included with a mean follow-up up of 2.12 (range, 1.00-4.98) years. Data collected included demographics, medical comorbidities, treatment history, complications and reoperation rates, patient-reported outcome measures (eg, Foot and Ankle Outcome Score), and opioid exposure.ResultsThere were significantly more complications among opioid exposed patients than opioid naïve ones (exposed = 29.41%, naïve = 9.62%; P = .044). Preoperative opioid exposure significantly correlated with postoperative opioid exposure (90-day: r = .903, p < .001; 180-day: r = .805, p < .001), and increased hospital length of stay (r = .263, p = .029). Furthermore, body mass index was a significant predictor of postoperative opioid exposure (90-day: r = .262, p = .013; 180-day: r = .217, p = .021), as was concomitant mental illness (90-day: r = .225, p = .035).ConclusionPatients with preoperative opioid exposure have significantly more complications and increased postoperative opioid exposure after foot and ankle surgery.Levels of Evidence:Level III: Retrospective cohort study.

术前阿片类药物治疗与足踝关节手术并发症发生率增加相关
本研究的目的是确定术前有阿片类药物使用史的患者在接受前足、后足或踝关节手术后,术后阿片类药物使用和并发症的可能性是否会增加。方法回顾性分析2015 - 2020年间某学术医疗中心一名奖学金培训的骨科足踝外科医生的前足、后足和踝关节手术情况。共纳入326例患者(356英尺),平均随访时间为2.12年(范围1.00-4.98)。收集的数据包括人口统计学、医疗合并症、治疗史、并发症和再手术率、患者报告的结果测量(如足部和踝关节结果评分)和阿片类药物暴露。结果阿片类药物暴露组并发症发生率明显高于阿片类药物naïve暴露组(暴露组= 29.41%,naïve = 9.62%;P = .044)。术前阿片类药物暴露与术后阿片类药物暴露显著相关(90天:r = .903, p < .001;180天:r = .805, p < .001),住院时间增加(r = .263, p = .029)。此外,体重指数是术后阿片类药物暴露的重要预测指标(90天:r = 0.262, p = 0.013;180天:r = 0.217, p = 0.021),同时伴有精神疾病(90天:r = 0.225, p = 0.035)。结论术前有阿片类药物暴露的患者并发症明显增多,且足踝关节手术后阿片类药物暴露增加。证据等级:III级:回顾性队列研究。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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