Recent advances in oxidative phenol coupling for the total synthesis of natural products

IF 10.2 1区化学 Q1 BIOCHEMISTRY & MOLECULAR BIOLOGY

Natural Product Reports Pub Date : 2024-02-21 DOI:10.1039/d3np00009e

Matthew C. Carson , Marisa C. Kozlowski

引用次数: 0

Abstract

Covering: 2008 to 2023

This review will describe oxidative phenol coupling as applied in the total synthesis of natural products. This review covers catalytic and electrochemical methods with a brief comparison to stoichiometric and enzymatic systems assessing their practicality, atom economy, and other measures. Natural products forged by C–C and C–O oxidative phenol couplings as well as from alkenyl phenol couplings will be addressed. Additionally, exploration into catalytic oxidative coupling of phenols and other related species (carbazoles, indoles, aryl ethers, etc.) will be surveyed. Future directions of this particular area of research will also be assessed.

Abstract Image

查看原文本刊更多论文

氧化苯酚偶联在天然产物全合成中的研究进展。

综述了氧化苯酚偶联在天然产物全合成中的应用。本文综述了催化和电化学方法，并与化学计量学和酶学系统进行了简要比较，评估了它们的实用性、原子经济性和其他措施。将讨论C-C和C-O氧化苯酚偶联以及烯基苯酚偶联形成的天然产物。此外，还将对苯酚和其他相关物质(咔唑、吲哚、芳醚等)的催化氧化偶联进行探索。还将评估这一特定研究领域的未来方向。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Natural Product Reports 化学-生化与分子生物学

CiteScore

21.20

自引率

3.40%

发文量

127

审稿时长

1.7 months

期刊介绍： Natural Product Reports (NPR) serves as a pivotal critical review journal propelling advancements in all facets of natural products research, encompassing isolation, structural and stereochemical determination, biosynthesis, biological activity, and synthesis. With a broad scope, NPR extends its influence into the wider bioinorganic, bioorganic, and chemical biology communities. Covering areas such as enzymology, nucleic acids, genetics, chemical ecology, carbohydrates, primary and secondary metabolism, and analytical techniques, the journal provides insightful articles focusing on key developments shaping the field, rather than offering exhaustive overviews of all results. NPR encourages authors to infuse their perspectives on developments, trends, and future directions, fostering a dynamic exchange of ideas within the natural products research community.