Surgical technique and preliminary results of a moulded, mobile spacer for the treatment of periprosthetic joint infection of the knee.

IF 1 4区 医学 Q3 ORTHOPEDICS
Operative Orthopadie Und Traumatologie Pub Date : 2023-06-01 Epub Date: 2023-04-03 DOI:10.1007/s00064-023-00803-z
Max Jaenisch, Mari Babasiz, Soufian Ben Amar, Eva Lück, Martin Gathen, Dieter Christian Wirtz, Thomas Martin Randau
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引用次数: 0

Abstract

Objective: Mobile knee spacers can be utilized in the first stage of a two-stage exchange in periprosthetic joint infection or septic arthritis of the knee to prevent soft tissue contraction, enable local antibiotic elution, and improve patient mobility. Commercially made moulds enable the surgeon to prepare a reproducible spacer design and match the preparation of the arthroplasty, which will be carried out in a second step.

Indications: Periprosthetic joint infection of the knee and severe cases of septic arthritis of the knee with advanced destruction/infiltration of the cartilage.

Contraindications: Antibiotic resistance of the microbiological pathogen to available antibiotic agents, incompliant patient, large osseous defect preventing proper fixation, known allergy to polymethylmethacrylate (PMMA) or antibiotic, severe soft tissue damage with high ligament instability, especially deterioration of extensor mechanism and insufficient patella/quadricep tendon.

Surgical technique: After thorough debridement and removal of all foreign material, cutting blocks are used to shape femur and tibia to the implant design required. Using a silicone mould, PMMA with suitable antibiotics is moulded into the shape of the future implant. After polymerization, the implants are fixed onto the bone with additional PMMA without pressurize for the sake of easy removal.

Postoperative management: Partial weight bearing with no restriction of flexion/extension while spacer is in place; second stage reimplantation as soon as infection is controlled.

Results: In all, 22 cases were treated, mostly with a PMMA spacer containing gentamicin and vancomycin. Pathogens were detected in 13 of 22 cases (59%). We observed two complications (9%). Twenty of 22 patients (86%) were reimplanted with a new arthroplasty; 16 of the 20 patients remained revision-free and infection-free at the last follow-up (average time to follow-up 13 months, range 1-46 months). Average range of motion in flexion and extension at follow-up was 98°.

模制可移动垫片治疗膝关节假体周围感染的外科技术和初步结果。
目的:在膝关节假体周围关节感染或感染性关节炎的两阶段交换的第一阶段,可以使用移动式膝关节垫片来防止软组织收缩,使局部抗生素洗脱,并提高患者的行动能力。商业制造的模具使外科医生能够准备可重复的垫片设计,并与将在第二步进行的关节成形术的准备相匹配。适应症:膝关节假体周围感染和严重的膝关节感染性关节炎,伴有软骨的晚期破坏/浸润。禁忌症:微生物病原体对可用抗生素制剂的抗生素耐药性,不合格的患者,无法正确固定的大骨缺损,已知对聚甲基丙烯酸甲酯(PMMA)或抗生素过敏,严重的软组织损伤伴高度韧带不稳,尤其是伸肌机制恶化和髌骨/股四肌腱不足。手术技术:在彻底清创并清除所有异物后,使用切割块将股骨和胫骨整形为所需的植入物设计。使用硅胶模具,将含有合适抗生素的PMMA模制成未来植入物的形状。聚合后,为了便于移除,用额外的PMMA在没有加压的情况下将植入物固定在骨上。术后处理:部分负重,无屈曲/伸展限制,同时放置垫片;第二阶段感染得到控制后立即重新种植。结果:总共有22例患者接受了治疗,大部分患者使用了含有庆大霉素和万古霉素的PMMA间隔物。22例中有13例(59%)检出病原体。我们观察到两种并发症(9%)。22名患者中有20名(86%)重新植入了新的关节成形术;20名患者中有16名在最后一次随访时保持无翻修和无感染(平均随访时间为13个月,范围为1-46个月)。随访时屈伸的平均活动范围为98°。
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来源期刊
CiteScore
2.10
自引率
0.00%
发文量
32
审稿时长
>12 weeks
期刊介绍: Orthopedics and Traumatology is directed toward all orthopedic surgeons, trauma-tologists, hand surgeons, specialists in sports injuries, orthopedics and rheumatology as well as gene-al surgeons who require access to reliable information on current operative methods to ensure the quality of patient advice, preoperative planning, and postoperative care. The journal presents established and new operative procedures in uniformly structured and extensively illustrated contributions. All aspects are presented step-by-step from indications, contraindications, patient education, and preparation of the operation right through to postoperative care. The advantages and disadvantages, possible complications, deficiencies and risks of the methods as well as significant results with their evaluation criteria are discussed. To allow the reader to assess the outcome, results are detailed and based on internationally recognized scoring systems. Orthopedics and Traumatology facilitates effective advancement and further education for all those active in both special and conservative fields of orthopedics, traumatology, and general surgery, offers sup-port for therapeutic decision-making, and provides – more than 30 years after its first publication – constantly expanding and up-to-date teaching on operative techniques.
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