Plasma activated Ringer's lactate solution.

IF 3.6 3区 生物学 Q2 BIOCHEMISTRY & MOLECULAR BIOLOGY
Hiromasa Tanaka, Masaaki Mizuno, Kenji Ishikawa, Camelia Miron, Yasumasa Okazaki, Shinya Toyokuni, Kae Nakamura, Hiroaki Kajiyama, Masaru Hori
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引用次数: 0

Abstract

Low-temperature plasma (LTP) has been widely used in life science. Plasma-activated solutions were defined as solutions irradiated with LTP, and water, medium, and Ringer's solutions have been irradiated with LTP to produce plasma-activated solutions. They contain chemical compounds produced by reactions among LTP, air, and solutions. Reactive oxygen and nitrogen species (RONS) are major components in plasma-activated solutions and recent studies revealed that plasma-activated organic compounds are produced in plasma-activated Ringer's lactate solution (PAL). Many in vitro and in vivo studies demonstrated that PAL exhibits anti-tumor effects on cancers, and biochemical analyses revealed intracellular molecular mechanisms of cancer cell death by PAL.

血浆激活林格氏乳酸溶液。
低温等离子体在生命科学中有着广泛的应用。等离子体活化溶液被定义为用LTP照射的溶液,用LTP照射水、介质和林格溶液产生等离子体活化溶液。它们含有LTP、空气和溶液之间反应产生的化合物。活性氧和活性氮(RONS)是等离子体活化溶液的主要成分,近年来的研究表明,等离子体活化的乳酸林格溶液(PAL)中产生了等离子体活化的有机化合物。许多体外和体内研究表明PAL对癌症具有抗肿瘤作用,生化分析揭示了PAL对癌细胞死亡的细胞内分子机制。
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来源期刊
Free Radical Research
Free Radical Research 生物-生化与分子生物学
CiteScore
6.70
自引率
0.00%
发文量
47
审稿时长
3 months
期刊介绍: Free Radical Research publishes high-quality research papers, hypotheses and reviews in free radicals and other reactive species in biological, clinical, environmental and other systems; redox signalling; antioxidants, including diet-derived antioxidants and other relevant aspects of human nutrition; and oxidative damage, mechanisms and measurement.
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