Cochlear Function in Adults Exposed to Severe Acute Respiratory Syndrome Coronavirus 2.

IF 1.6 4区医学 Q2 AUDIOLOGY & SPEECH-LANGUAGE PATHOLOGY

Audiology and Neuro-Otology Pub Date : 2023-01-01 DOI:10.1159/000527811

Betul Cicek Cinar, Beyza Demirtas, Mehmet Can, Ibrahim Emir Yesil, Munir Demir Bajin

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Abstract

Introduction: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a viral infection with a wide variety of symptoms, including fever, coughing, sneezing, fatigue, and a loss of taste and smell. Moreover, there are some recent studies that investigate the effects of SARS-CoV-2 on hearing and auditory performance. With this current study, we investigate the early effects of the coronavirus disease on hair cells in the cochlea.

Methods: In the current study, there were 25 subjects (17 females, 8 males) who tested positive for polymerase chain reaction on nasopharyngeal swabs. They had reported normal auditory functions and no history of otology before SARS-CoV-2. To determine auditory functions, pure-tone audiometry, otoacoustic emissions (OAE) tests, and threshold equalizing noise (TEN) tests were used.

Results: Although the hearing thresholds increased at higher frequencies, they were within normal limits according to four-frequency pure-tone averages. All participants had normal OAE, and there were no detected dead regions for any of the subjects. Even so, there were significant increases in hearing thresholds in TEN.

Conclusion: There is no cochlear dysfunction discovered by OAE and TEN in SARS-CoV-2-affected individuals. Nonetheless, the increase in hearing thresholds at higher frequencies, other than the pure-tone average frequencies detected by TEN, and the decrease in the presence of detected OAE could be related to deterioration in the basal part of the cochlea.

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暴露于严重急性呼吸综合征冠状病毒的成人耳蜗功能研究

简介:严重急性呼吸综合征冠状病毒2 (SARS-CoV-2)是一种具有多种症状的病毒感染，包括发烧、咳嗽、打喷嚏、疲劳以及味觉和嗅觉丧失。此外，最近有一些研究调查了SARS-CoV-2对听力和听觉表现的影响。在目前的研究中，我们研究了冠状病毒病对耳蜗毛细胞的早期影响。方法:本研究共收集鼻咽拭子聚合酶链反应阳性25例(女17例，男8例)。他们报告的听力功能正常，在SARS-CoV-2之前没有耳科病史。为了确定听觉功能，使用纯音测听、耳声发射(OAE)测试和阈值均衡噪声(TEN)测试。结果:高频听力阈值升高，但四频纯音平均值在正常范围内。所有参与者都有正常的OAE，并且没有检测到任何受试者的死区。即便如此，TEN的听力阈值仍有显著提高。结论:sars - cov -2感染人群经OAE和TEN检测未发现耳蜗功能障碍。尽管如此，除TEN检测到的纯音平均频率外，更高频率的听力阈值升高，以及检测到的OAE存在的减少可能与耳蜗基底部的恶化有关。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Audiology and Neuro-Otology 医学-耳鼻喉科学

CiteScore

3.20

自引率

6.20%

发文量

审稿时长

>12 weeks

期刊介绍： ''Audiology and Neurotology'' provides a forum for the publication of the most-advanced and rigorous scientific research related to the basic science and clinical aspects of the auditory and vestibular system and diseases of the ear. This journal seeks submission of cutting edge research opening up new and innovative fields of study that may improve our understanding and treatment of patients with disorders of the auditory and vestibular systems, their central connections and their perception in the central nervous system. In addition to original papers the journal also offers invited review articles on current topics written by leading experts in the field. The journal is of primary importance for all scientists and practitioners interested in audiology, otology and neurotology, auditory neurosciences and related disciplines.