Atrial fibrillation increases the risk of new-onset myocardial infarction amongst working-age population: a propensity-matched study.

IF 1.1 4区医学 Q4 CARDIAC & CARDIOVASCULAR SYSTEMS

Herz Pub Date : 2023-10-01 Epub Date: 2023-06-01 DOI:10.1007/s00059-023-05181-7

Bocheng Yue, Qiqi Hou, Julian Bredehorst, Quanle Han, Boheng Zhang, Chao Zhang, Jiawei Zhang, Shuohua Chen, Shouling Wu, Kangbo Li

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引用次数: 0

Abstract

Objective: The aim of this study was to investigate the association between atrial fibrillation (AF) and new-onset myocardial infarction (MI) among a working-age population in an industrial city of North China.

Methods: In total 77,670 participants aged under 60 years were selected for this cohort study. Participants were divided into an AF group (n = 121) and a non-AF group (n = 74,565) based on their medical histories. Thereafter, 121 participants from the AF group were propensity-matched with 363 participants from the non-AF group. All participants were followed up from June 2006 to December 2020; new-onset MI was regarded as the endpoint of this study. Multivariate Cox proportional hazards regression analysis models were designed to analyze the correlation between AF and new-onset MI.

Results: During the 14-year follow-up, eight cases of new-onset MI were documented in the AF group, while five cases were documented in the non-AF group. The cumulative incidence of new-onset MI in the AF group (7.40%) was markedly higher than in the non-AF group (1.41%; p < 0.001). Atrial fibrillation was associated with an increased risk of new-onset MI in both univariate analysis (hazard ratio: 5.202, 95% confidence interval [CI]: 1.700-15.913) and multivariable-adjusted analysis (hazard ratio: 5.335, 95% CI: 1.683-16.910).

Conclusion: Atrial fibrillation increased the risk of new-onset MI amongst working-age individuals in an industrial city of North China.

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工作年龄人群中心房颤动增加新发心肌梗死的风险：一项倾向匹配研究。

目的：研究华北某工业城市工作年龄人群心房颤动（AF）与新发心肌梗死（MI）的关系。参与者被分为AF组（n = 121）和非AF组（n = 74565）。此后，来自AF组的121名参与者与来自非AF组的363名参与者进行倾向匹配。2006年6月至2020年12月对所有参与者进行了随访；新发MI被视为本研究的终点。设计了多变量Cox比例风险回归分析模型来分析房颤和新发MI之间的相关性。结果：在14年的随访中，房颤组记录了8例新发MI，而非房颤组则记录了5例。AF组新发MI的累计发生率（7.40%）明显高于非AF组（1.41%；p 结论：在中国北方某工业城市的工作年龄人群中，心房颤动增加了新发MI的风险。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Herz 医学-心血管系统

CiteScore

3.00

自引率

5.90%

发文量

审稿时长

4-8 weeks

期刊介绍： Herz is the high-level journal for further education for all physicians interested in cardiology. The individual issues of the journal each deal with specific topics and comprise review articles in English and German written by competent and esteemed authors. They provide up-to-date and comprehensive information concerning the speciality dealt with in the issue. Due to the fact that all relevant aspects of the pertinent topic of an issue are considered, an overview of the current status and progress in cardiology is presented. Reviews and original articles round off the spectrum of information provided.