[POST-ARTEMISININ DELAYED HEMOLYSIS AFTER TREATMENT OF MALARIA].

Harefuah Pub Date : 2023-03-01
Nadav Baharav, Eli Schwartz
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Abstract

Introduction: Falciparum malaria is highly endemic in sub-Saharan Africa. The disease is caused by the intra-cellular parasite Plasmodium within erythrocytes. The recommended treatment is artemisinin-based combination which is efficient and safe. In some patients, artemisinin can cause hemolysis weeks after treatment, presenting with severe anemia. Most of the published cases were following intravenous treatment. We present a case of a falciparum malaria patient with hemolysis and severe anemia two weeks after oral treatment with artemisinin-based combination therapy.

[使用青蒿素后疟疾治疗后延迟溶血]。
恶性疟疾在撒哈拉以南非洲地区高度流行。这种疾病是由红细胞内的细胞内寄生虫疟原虫引起的。建议采用以青蒿素为基础的复方治疗,既有效又安全。在一些患者中,青蒿素可在治疗数周后引起溶血,表现为严重贫血。大多数公布的病例都是静脉注射治疗。我们提出一个病例恶性疟疾患者溶血和严重贫血两周后口服治疗青蒿素为基础的联合治疗。
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