Nanotheranostics: application of nanosensors in diabetes management.

IF 1.8 Q4 ENDOCRINOLOGY & METABOLISM

Journal of Diabetes and Metabolic Disorders Pub Date : 2023-03-17 eCollection Date: 2023-06-01 DOI:10.1007/s40200-023-01206-4

Kalyani Pathak, Riya Saikia, Himangshu Sarma, Manash Pratim Pathak, Ratna Jyoti Das, Urvashee Gogoi, Mohammad Zaki Ahmad, Aparoop Das, Basel A Abdel Wahab

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引用次数: 0

Abstract

Objectives: The objective of the present study is to discuss the use of nanomaterials like nanosensors for diagnosing Diabetes and highlight their applications in the treatment of Diabetes.

Methods: Diabetes mellitus (D.M.) is a group of metabolic diseases characterized by hyperglycemia. Orally administered antidiabetic drugs like glibenclamide, glipalamide, and metformin can partially lower blood sugar levels, but long-term use causes kidney and liver damage. Recent breakthroughs in nanotheranostics have emerged as a powerful tool for diabetes treatment and diagnosis.

Results: Nanotheranostics is a rapidly developing area that can revolutionize diabetes diagnosis and treatment by combining therapy and imaging in a single probe, allowing for pancreas-specific drug and insulin delivery. Nanotheranostic in Diabetes research has facilitated the development of improved glucose monitoring and insulin administration modalities, which promise to improve the quality of life for people with Diabetes drastically. Further, nanomaterials like nanocarriers and unique functional nanomaterials used as nano theranostics tools for treating Diabetes will also be highlighted.

Conclusion: The nanosensors discussed in this review article will encourage researchers to develop innovative nanomaterials with novel functionalities and properties for diabetes detection and treatment.

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纳米技术：纳米传感器在糖尿病管理中的应用。

目的：本研究的目的是讨论纳米材料（如纳米传感器）在糖尿病诊断中的应用，并强调其在糖尿病治疗中的应用。方法：糖尿病是一组以高血糖为特征的代谢性疾病。口服抗糖尿病药物，如格列本脲、格列帕胺和二甲双胍，可以部分降低血糖水平，但长期使用会导致肾脏和肝脏损伤。纳米治疗学的最新突破已成为糖尿病治疗和诊断的有力工具。结果：纳米技术是一个快速发展的领域，通过将治疗和成像结合在一个探针中，可以实现胰腺特异性药物和胰岛素递送，可以彻底改变糖尿病的诊断和治疗。糖尿病研究中的纳米技术促进了改进血糖监测和胰岛素给药模式的发展，有望大幅提高糖尿病患者的生活质量。此外，还将重点介绍纳米载体等纳米材料和用作治疗糖尿病的纳米治疗工具的独特功能纳米材料。结论：这篇综述文章中讨论的纳米传感器将鼓励研究人员开发具有新功能和特性的创新纳米材料，用于糖尿病检测和治疗。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Diabetes and Metabolic Disorders Medicine-Internal Medicine

CiteScore

4.80

自引率

3.60%

发文量

210

期刊介绍： Journal of Diabetes & Metabolic Disorders is a peer reviewed journal which publishes original clinical and translational articles and reviews in the field of endocrinology and provides a forum of debate of the highest quality on these issues. Topics of interest include, but are not limited to, diabetes, lipid disorders, metabolic disorders, osteoporosis, interdisciplinary practices in endocrinology, cardiovascular and metabolic risk, aging research, obesity, traditional medicine, pychosomatic research, behavioral medicine, ethics and evidence-based practices.As of Jan 2018 the journal is published by Springer as a hybrid journal with no article processing charges. All articles published before 2018 are available free of charge on springerlink.Unofficial 2017 2-year Impact Factor: 1.816.