An Overview of Pharmacotherapy in the Management of Children with Autism Spectrum Disorder at a Public Hospital in KwaZulu-Natal.

IF 2.3 3区 医学 Q2 PSYCHIATRY
Child Psychiatry & Human Development Pub Date : 2024-12-01 Epub Date: 2023-03-22 DOI:10.1007/s10578-023-01514-z
Jennal Maniram, Frasia Oosthuizen, Saira B S Karrim
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引用次数: 0

Abstract

This study presents an overview of prescribing patterns and provides insight into the current management practice for the core symptoms and comorbidities of ASD in children. A quantitative retrospective study was conducted at a public hospital in KwaZulu-Natal, South Africa by reviewing patient files of children diagnosed with ASD and meeting the inclusion criteria for the study. A descriptive analysis of data was done to identify treatment trends and patient therapeutic outcomes. A total of 181 children met the inclusion criteria of the study. Risperidone was the most frequently prescribed drug (88%) for the management of comorbidities and/or core symptoms of ASD. Drugs prescribed to manage ASD comorbidities included methylphenidate, melatonin, sodium valproate, risperidone, oxybutynin, carbamazepine, and others. Except for risperidone, there were no additional drugs that targeted the core symptoms of ASD. Non-pharmacological therapies were often used collaboratively with medication to manage ASD symptoms. In 41% of patients, there were improvements in their symptoms.

夸祖鲁-纳塔尔省一家公立医院治疗自闭症谱系障碍儿童的药物疗法概述。
本研究概述了处方模式,并深入探讨了当前针对儿童自闭症核心症状和合并症的管理实践。本研究在南非夸祖鲁-纳塔尔省的一家公立医院进行了一项定量回顾性研究,查阅了被诊断患有自闭症并符合研究纳入标准的儿童患者档案。研究人员对数据进行了描述性分析,以确定治疗趋势和患者的治疗效果。共有 181 名儿童符合研究的纳入标准。利培酮是治疗 ASD 合并症和/或核心症状的最常用处方药(88%)。用于治疗 ASD 并发症的处方药包括哌醋甲酯、褪黑素、丙戊酸钠、利培酮、奥布宁、卡马西平等。除利培酮外,没有针对 ASD 核心症状的其他药物。非药物疗法通常与药物治疗同时使用,以控制 ASD 症状。41%的患者症状有所改善。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
0.50
自引率
3.40%
发文量
174
期刊介绍: Child Psychiatry & Human Development is an interdisciplinary international journal serving the groups represented by child and adolescent psychiatry, clinical child/pediatric/family psychology, pediatrics, social science, and human development. The journal publishes research on diagnosis, assessment, treatment, epidemiology, development, advocacy, training, cultural factors, ethics, policy, and professional issues as related to clinical disorders in children, adolescents, and families. The journal publishes peer-reviewed original empirical research in addition to substantive and theoretical reviews.
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