Nanoparticles as a Therapeutic Delivery System for Skin Cancer Prevention and Treatment

Jungsoo Chang , Beverly Yu , W. Mark Saltzman , Michael Girardi
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引用次数: 2

Abstract

The use of nanoparticles (NPs) as a therapeutic delivery system has expanded markedly over the past decade, particularly regarding applications targeting the skin. The delivery of NP-based therapeutics to the skin requires special consideration owing to its role as both a physical and immunologic barrier, and specific technologies must not only take into consideration the target but also the pathway of delivery. The unique challenge this poses has been met with the development of a wide panel of NP-based technologies meant to precisely address these considerations. In this review article, we describe the application of NP-based technologies for drug delivery targeting the skin, summarize the types of NPs, and discuss the current landscape of NPs for skin cancer prevention and skin cancer treatment as well as future directions within these applications.

Abstract Image

Abstract Image

纳米粒子作为预防和治疗皮肤癌的治疗递送系统
在过去的十年里,纳米颗粒(NP)作为治疗递送系统的用途显著扩大,特别是在针对皮肤的应用方面。基于NP的治疗剂对皮肤的递送需要特别考虑,因为它既是物理屏障又是免疫屏障,特定技术不仅必须考虑靶点,还必须考虑递送途径。这带来的独特挑战已经随着一系列基于NP的技术的发展而得到了满足,这些技术旨在准确地解决这些问题。在这篇综述文章中,我们描述了基于NP的皮肤给药技术的应用,总结了NP的类型,并讨论了NP在皮肤癌症预防和皮肤癌症治疗方面的现状以及这些应用的未来方向。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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