The genetic structure and admixture of Manchus and Koreans in northeast China.

IF 1.2 4区医学 Q2 ANTHROPOLOGY

Annals of Human Biology Pub Date : 2023-02-01 DOI:10.1080/03014460.2023.2182912

Na Sun, Le Tao, Rui Wang, Kongyang Zhu, Xiangjun Hai, Chuan-Chao Wang

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引用次数: 1

Abstract

Background: The fine-scale genetic profiles and population history of Manchus and Koreans remain unclear.

Aim: To infer a fine-scale genetic structure and admixture of Manchu and Korean populations.

Subjects and methods: We collected and genotyped 16 Manchus from Liaoning and 18 Koreans from Jilin province with about 700K genome-wide SNPs. We analysed the data using principal component analysis (PCA), ADMIXTURE, Fst, TreeMix, f-statistics, qpWave, and qpAdm.

Results: Manchus and Koreans showed a genetic affinity with northern East Asians. Chinese Koreans showed a long-term genetic continuity with Bronze Age populations from the West Liao River and had a strong affinity with Koreans in South Korea and Japan. Manchus had a different genetic profile compared with other Tungusic populations since the Manchus received additional genetic influence from the southern Chinese but didn't have West Eurasian-related admixture.

Conclusions: The genetic formation of Manchus involving southern Chinese was consistent with the extensive interactions between Manchus and populations from central and southern China. The large-scale genetic continuity between ancient West Liao River farmers and Koreans highlighted the role farming expansion played in the peopling of the Korean Peninsula.

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中国东北满族与朝鲜族的遗传结构及其混种。

背景:满族和朝鲜族的精细遗传谱和种群历史尚不清楚。目的:推测满族和朝鲜族人群的精细遗传结构和混种。对象与方法:收集了来自辽宁的16名满族人和来自吉林的18名朝鲜族人的全基因组snp约700K，并进行了基因分型。我们使用主成分分析(PCA)、admix、Fst、TreeMix、f-statistics、qpWave和qpAdm对数据进行分析。结果:满族和朝鲜族与东亚北部人有亲缘关系。中国朝鲜族与西辽河青铜器时代的朝鲜族有长期的遗传连续性，与韩国和日本的朝鲜族有很强的亲缘关系。与其他通古斯人相比，满族人具有不同的遗传特征，因为满族人从中国南方获得了额外的遗传影响，但没有与欧亚西部有关的混合。结论:南方满人的遗传形成与满人与中国中部和南部人群的广泛相互作用是一致的。古代西辽河农民和朝鲜人之间的大规模遗传连续性突出了农业扩张在朝鲜半岛人口定居中所起的作用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Annals of Human Biology 生物-公共卫生、环境卫生与职业卫生

CiteScore

3.40

自引率

5.90%

发文量

审稿时长

1 months

期刊介绍： Annals of Human Biology is an international, peer-reviewed journal published six times a year in electronic format. The journal reports investigations on the nature, development and causes of human variation, embracing the disciplines of human growth and development, human genetics, physical and biological anthropology, demography, environmental physiology, ecology, epidemiology and global health and ageing research.