Increasing the stability of incense gum extract (Styrax benzoin) with a mixture of surfactants.

IF 1.4 Q3 Pharmacology, Toxicology and Pharmaceutics
Nora Susanti, Jamalum Purba, M Yosia Gopas Oetama
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引用次数: 0

Abstract

Styrax benzoin is a type of incense produced in North Tapanuli, Indonesia. The content of metabolite compounds provides wide use in pharmaceuticals. The occurrence of deposits in the extract makes this preparation unstable; this instability creates problems, especially in the concentration of the extract and is impractical so it needs to be redissolved. The method of using surfactants can be used as a suspending agent, a mixture of two types of surfactants gives variations in hydrophilic and lipophilic balance (HLB), by finding the optimum HLB value to create optimum solution stability and organoleptic, various mixture ratios were carried out with test parameters such as organoleptic, pH, viscosity, particle size, and components of chemical compounds. The results show that the optimum HLB of S. benzoin is 12.7 in surfactants Tween 80 and Span 80.

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用表面活性剂混合物提高香胶提取物(安息香)的稳定性。
安息香是一种产于印度尼西亚北塔帕努利的熏香。代谢产物化合物的含量在药物中提供了广泛的用途。提取物中沉积物的出现使该制剂不稳定;这种不稳定性会产生问题,特别是在提取物的浓度方面,而且不切实际,因此需要重新解决。使用表面活性剂的方法可以用作悬浮剂,两种类型的表面活性剂混合物在亲水性和亲脂性平衡(HLB)方面产生变化,通过找到最佳的HLB值来产生最佳的溶液稳定性和感官,用感官、pH、粘度、粒径、,以及化合物的成分。结果表明,苯偶姻在表面活性剂Tween 80和Span 80中的最适HLB为12.7。
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来源期刊
CiteScore
2.00
自引率
7.10%
发文量
44
审稿时长
20 weeks
期刊介绍: Journal of Advanced Pharmaceutical Technology & Research (JAPTR) is an Official Publication of Society of Pharmaceutical Education & Research™. It is an international journal published Quarterly. Journal of Advanced Pharmaceutical Technology & Research (JAPTR) is available in online and print version. It is a peer reviewed journal aiming to communicate high quality original research work, reviews, short communications, case report, Ethics Forum, Education Forum and Letter to editor that contribute significantly to further the scientific knowledge related to the field of Pharmacy i.e. Pharmaceutics, Pharmacology, Pharmacognosy, Pharmaceutical Chemistry. Articles with timely interest and newer research concepts will be given more preference.
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