Clinical Features, Socioeconomic Status, Management, and Outcomes of Acute Heart Failure: PEACE MENA Registry Phase I Results.

IF 2.8 3区医学 Q2 PERIPHERAL VASCULAR DISEASE

Current vascular pharmacology Pub Date : 2023-01-01 DOI:10.2174/1570161121666230525111259

Hanan AlBackr, Khalid F Alhabib, Kadhim Sulaiman, Amal Jamee, Mohamed Sobhy, Salim Benkhedda, Sobhi Dada, Ayman Hammoudeh, Habib Gamra, Ahmed Al-Motarreb, Fahad Alkindi, Mohammad I Amin, Magdi G Yousif, Hasan A Farhan, Nadia Fellat, Wael Almahmeed, Mohammad Al Jarallah, Prashanth Panduranga, Magdy Abdelhamid, Ihab Ghaly, Dahlia Djermane, Ahcene Chibane, Hadi Skouri, Mohamad Jarrah, Hassen Amor, Nora K Alsagheer, Mohammed A Hozayen, Hosameldin S Ahmed, Muhammad Ali, Anhar Ullah, Ayman Al Saleh, Faiez Zannad

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引用次数: 0

Abstract

Introduction: PEACE MENA (Program for the Evaluation and Management of Cardiac Events in the Middle East and North Africa) is a prospective registry in Arab countries for in-patients with acute myocardial infarction (AMI) or acute heart failure (AHF). Here, we report the baseline characteristics and outcomes of in-patients with AHF who were enrolled during the first 14 months of the recruitment phase.

Methods: A prospective, multi-centre, multi-country study including patients hospitalized with AHF was conducted. Clinical characteristics, echocardiogram, BNP (B-type natriuretic peptide), socioeconomic status, management, 1-month, and 1-year outcomes are reported.

Results: Between April 2019 and June 2020, a total of 1258 adults with AHF from 16 Arab countries were recruited. Their mean age was 63.3 (±15) years, 56.8% were men, 65% had monthly income ≤US$ 500, and 56% had limited education. Furthermore, 55% had diabetes mellitus, 67% had hypertension; 55% had HFrEF (heart failure with reduced ejection fraction), and 19% had HFpEF (heart failure with preserved ejection fraction). At 1 year, 3.6% had a heart failure-related device (0-22%) and 7.3% used an angiotensin receptor neprilysin inhibitor (0-43%). Mortality was 4.4% per 1 month and 11.77% per 1-year post-discharge. Compared with higher-income patients, lower-income patients had a higher 1-year total heart failure hospitalization rate (45.6 vs 29.9%, p=0.001), and the 1-year mortality difference was not statistically significant (13.2 vs 8.8%, p=0.059).

Conclusion: Most of the patients with AHF in Arab countries had a high burden of cardiac risk factors, low income, and low education status with great heterogeneity in key performance indicators of AHF management among Arab countries.

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急性心力衰竭的临床特征、社会经济状况、管理和结果：PEACE中东和北非注册中心I期结果。

简介：中东和北非心脏事件评估和管理计划（PEACE MENA）是阿拉伯国家急性心肌梗死（AMI）或急性心力衰竭（AHF）住院患者的前瞻性登记。在这里，我们报告了在招募阶段的前14个月内登记的AHF住院患者的基线特征和结果。方法：进行一项前瞻性、多中心、多国家的研究，包括因AHF住院的患者。报告了临床特征、超声心动图、BNP（B型钠尿肽）、社会经济状况、管理、1个月和1年的结果。结果：2019年4月至2020年6月，共招募了来自16个阿拉伯国家的1258名患有AHF的成年人。他们的平均年龄为63.3（±15）岁，56.8%为男性，65%的人月收入≤500美元，56%的人受教育程度有限。此外，55%患有糖尿病，67%患有高血压；55%患有HFrEF（射血分数降低的心力衰竭），19%患有HFpEF（射气分数保持的心力衰竭）。1年时，3.6%的患者使用了心力衰竭相关装置（0-22%），7.3%的患者使用血管紧张素受体奈普赖氨酸抑制剂（0-43%）。出院后1个月死亡率为4.4%，1年死亡率为11.77%。与高收入患者相比，低收入患者的1年总心力衰竭住院率较高（45.6vs29.9%，p=0.001），1年死亡率差异无统计学意义（13.2vs8.8%，p=0.059），阿拉伯国家受教育程度低，AHF管理的关键绩效指标存在很大的异质性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Current vascular pharmacology 医学-外周血管病

CiteScore

9.20

自引率

4.40%

发文量

审稿时长

6-12 weeks

期刊介绍： Current Vascular Pharmacology publishes clinical and research-based reviews/mini-reviews, original research articles, letters, debates, drug clinical trial studies and guest edited issues to update all those concerned with the treatment of vascular disease, bridging the gap between clinical practice and ongoing research. Vascular disease is the commonest cause of death in Westernized countries and its incidence is on the increase in developing countries. It follows that considerable research is directed at establishing effective treatment for acute vascular events. Long-term treatment has also received considerable attention (e.g. for symptomatic relief). Furthermore, effective prevention, whether primary or secondary, is backed by the findings of several landmark trials. Vascular disease is a complex field with primary care physicians and nurse practitioners as well as several specialties involved. The latter include cardiology, vascular and cardio thoracic surgery, general medicine, radiology, clinical pharmacology and neurology (stroke units).