Characteristics of Hearing Loss Among Older Adults in the Korean Genome and Epidemiology Study: A Community-Based Longitudinal Cohort Study With an 8-Year Follow-up.

IF 2.9 3区医学 Q1 OTORHINOLARYNGOLOGY

Clinical and Experimental Otorhinolaryngology Pub Date : 2023-05-01 DOI:10.21053/ceo.2022.01557

Kyoung Ho Oh, Hyunsan Cho, Seung Ku Lee, Chol Shin, June Choi

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Abstract

Objectives: This study investigated the 8-year incidence and progression of hearing loss (HL) and its types and examined the risk factors for changes in HL.

Methods: This longitudinal cohort study analyzed data from the Korean Genome and Epidemiology Study (KoGES), an ongoing, prospective, community-based cohort study that has been conducted since 2001. Altogether, 1,890 residents of urban areas in Korea aged 45-75 years at time 1 (baseline) were included in the study. Pure-tone audiometry (PTA) testing was performed twice, at time 1 (2008-2009) and time 2 (2015-2018, follow-up), 8 years apart. HL grades were defined as seven mutually exclusive categories following the revised World Health Organization classification. Incidence was defined as PTA >20 dB HL in the better ear at time 2 among those without HL at time 1. Progression was defined as the progressive deterioration of HL among those with HL at time 1. The three types of HL constituted sensorineural (SNHL), conductive, and mixed HL.

Results: At time 1, 36.40% of patients were diagnosed with HL, which increased to 51.64% at time 2. The 8-year incidence of HL was 27.20%, and progressive deterioration of HL occurred in 23.11% of those with HL. SNHL was the most common type of HL, and its prevalence markedly increased at time 2. Multivariate analysis demonstrated that the incidence of HL was significantly associated with increasing age, male sex (odds ratio [OR], 1.73; 95% confidence interval [CI], 1.07-2.81), and diabetes mellitus (OR, 1.43; 95% CI, 1.04-1.96). Alcohol consumption was a risk factor for HL deterioration among those with HL at time 1.

Conclusion: The prevalence and deterioration of HL were extremely high among older adults, and age was the strongest risk factor for these changes. Therefore, timely screening and intervention are necessary to prevent HL and delay its deterioration among older adults.

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韩国基因组和流行病学研究中老年人听力损失的特征:一项基于社区的纵向队列研究，随访8年。

目的:本研究调查了听力损失(HL)的8年发病率和进展及其类型，并探讨了HL变化的危险因素。方法:这项纵向队列研究分析了韩国基因组和流行病学研究(KoGES)的数据，这是一项正在进行的前瞻性社区队列研究，自2001年以来一直进行。总共有1890名在时间1(基线)时年龄在45-75岁的韩国城市地区居民被纳入研究。进行两次纯音听力学(PTA)测试，时间1(2008-2009年)和时间2(2015-2018年，随访)，间隔8年。根据世界卫生组织修订的分类，HL等级被定义为七个相互排斥的类别。在时间1时无HL的患者中，在时间2时较好耳中PTA >20 dB HL的发生率被定义为。进展被定义为在时间1时患有HL的患者中HL的逐渐恶化。三种类型的HL分别为感音神经性HL、导电性HL和混合性HL。结果:第1次诊断为HL的患者占36.40%，第2次诊断为51.64%。HL的8年发病率为27.20%，进行性恶化发生率为23.11%。SNHL是最常见的HL类型，其患病率在时间2时显著增加。多因素分析显示，HL的发病率与年龄、男性显著相关(优势比[OR]， 1.73;95%可信区间[CI]， 1.07-2.81)和糖尿病(OR, 1.43;95% ci, 1.04-1.96)。在时间1的HL患者中，饮酒是HL恶化的危险因素。结论:HL在老年人中的患病率和恶化程度极高，年龄是这些变化的最强危险因素。因此，及时筛查和干预是预防老年人HL并延缓其恶化的必要措施。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Clinical and Experimental Otorhinolaryngology 医学-耳鼻喉科学

CiteScore

4.90

自引率

6.70%

发文量

审稿时长

6-12 weeks

期刊介绍： Clinical and Experimental Otorhinolaryngology (Clin Exp Otorhinolaryngol, CEO) is an international peer-reviewed journal on recent developments in diagnosis and treatment of otorhinolaryngology-head and neck surgery and dedicated to the advancement of patient care in ear, nose, throat, head, and neck disorders. This journal publishes original articles relating to both clinical and basic researches, reviews, and clinical trials, encompassing the whole topics of otorhinolaryngology-head and neck surgery. CEO was first issued in 2008 and this journal is published in English four times (the last day of February, May, August, and November) per year by the Korean Society of Otorhinolaryngology-Head and Neck Surgery. The Journal aims at publishing evidence-based, scientifically written articles from different disciplines of otorhinolaryngology field. The readership contains clinical/basic research into current practice in otorhinolaryngology, audiology, speech pathology, head and neck oncology, plastic and reconstructive surgery. The readers are otolaryngologists, head and neck surgeons and oncologists, audiologists, and speech pathologists.