Enamel Fluoride Uptake Determined Using the Microbiopsy Technique and Time-of-Flight Secondary Ion Mass Spectrometry: A Pilot Study.

IF 2.9 2区医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE

Caries Research Pub Date : 2023-01-01 Epub Date: 2023-05-10 DOI:10.1159/000530709

Nicole Michler, Maria Morawietz, Stephan Gierth, Frank Lippert, Andreas Kiesow

引用次数: 0

Abstract

This study evaluated the suitability of time-of-flight secondary ion mass spectrometry (ToF-SIMS) to assess enamel fluoride uptake (EFU) in comparison with the microbiopsy technique. Enamel specimens were exposed to equimolar solutions of fluoride prepared from sodium fluoride (NaF), stannous fluoride (SnF2), or amine fluoride (AmF). EFU was quantified by both techniques on the same specimens. EFU was found to be highest for samples treated with AmF, followed by SnF2 and NaF. Both methods yielded clearly interpretable, highly correlating (r = 0.95) data. ToF-SIMS can be considered a promising alternative to the microbiopsy technique for near-surface EFU assessment.

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使用显微活检技术和飞行时间二次离子质谱测定牙釉质氟摄取:一项试点研究。

本研究评估了飞行时间二次离子质谱法(ToF-SIMS)与显微活检技术在评估牙釉质氟摄取(EFU)方面的适用性。釉质标本暴露于氟化钠(NaF)、氟化亚锡(SnF2)或氟化胺(AmF)配制的等摩尔氟溶液中。用两种技术对同一标本进行EFU定量。经AmF处理的样品EFU最高，其次是SnF2和NaF。两种方法都得到了清晰可解释、高度相关(r = 0.95)的数据。ToF-SIMS可以被认为是一种很有前途的替代近地表EFU评估的显微活检技术。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Caries Research 医学-牙科与口腔外科

CiteScore

6.30

自引率

7.10%

发文量

审稿时长

6-12 weeks

期刊介绍： ''Caries Research'' publishes epidemiological, clinical and laboratory studies in dental caries, erosion and related dental diseases. Some studies build on the considerable advances already made in caries prevention, e.g. through fluoride application. Some aim to improve understanding of the increasingly important problem of dental erosion and the associated tooth wear process. Others monitor the changing pattern of caries in different populations, explore improved methods of diagnosis or evaluate methods of prevention or treatment. The broad coverage of current research has given the journal an international reputation as an indispensable source for both basic scientists and clinicians engaged in understanding, investigating and preventing dental disease.