Giovanni Gherardi, Pier Luigi Surico, Marco Coassin, Antonio Di Zazzo, Silvia D'Arezzo, Silvia Angeletti, Carla Fontana, Nicola Petrosillo
{"title":"Meningococcal Conjunctivitis in a 54-Year-Old Man: Case Report and Review of the Literature.","authors":"Giovanni Gherardi, Pier Luigi Surico, Marco Coassin, Antonio Di Zazzo, Silvia D'Arezzo, Silvia Angeletti, Carla Fontana, Nicola Petrosillo","doi":"10.1159/000530894","DOIUrl":null,"url":null,"abstract":"<p><p>Neisseria meningitidis represents an uncommon pathogen of acute bacterial conjunctivitis. In this brief report, we describe a case of meningococcal conjunctivitis in an immunocompetent adult male, with a review of the literature. The patient went to the outpatient ophthalmology clinic complaining of severe ocular discomfort, burning, and redness for more than 2 weeks and, at slit lamp examination, he was diagnosed with a mild conjunctivitis. Microbiology cultures of ocular swabs revealed the growth of colonies, as pure culture, identified as N. meningitidis of serogroup B. A diagnosis of primary meningococcal conjunctivitis was made and treatment of patient with intramuscular injections of ceftriaxone in addition to topical moxifloxacin eye drops for 2 weeks led to clinical improvement and, finally, to a complete recovery, in accordance with microbiological findings. Ophthalmologists must be aware of the possibility of primary meningococcal conjunctivitis cases, even uncommon, and the need to treat with systemic antibiotics and their close contacts with adequate antibiotic chemoprophylaxis.</p>","PeriodicalId":2,"journal":{"name":"ACS Applied Bio Materials","volume":null,"pages":null},"PeriodicalIF":4.6000,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"ACS Applied Bio Materials","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1159/000530894","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2023/5/7 0:00:00","PubModel":"Epub","JCR":"Q2","JCRName":"MATERIALS SCIENCE, BIOMATERIALS","Score":null,"Total":0}
引用次数: 0
Abstract
Neisseria meningitidis represents an uncommon pathogen of acute bacterial conjunctivitis. In this brief report, we describe a case of meningococcal conjunctivitis in an immunocompetent adult male, with a review of the literature. The patient went to the outpatient ophthalmology clinic complaining of severe ocular discomfort, burning, and redness for more than 2 weeks and, at slit lamp examination, he was diagnosed with a mild conjunctivitis. Microbiology cultures of ocular swabs revealed the growth of colonies, as pure culture, identified as N. meningitidis of serogroup B. A diagnosis of primary meningococcal conjunctivitis was made and treatment of patient with intramuscular injections of ceftriaxone in addition to topical moxifloxacin eye drops for 2 weeks led to clinical improvement and, finally, to a complete recovery, in accordance with microbiological findings. Ophthalmologists must be aware of the possibility of primary meningococcal conjunctivitis cases, even uncommon, and the need to treat with systemic antibiotics and their close contacts with adequate antibiotic chemoprophylaxis.
脑膜炎奈瑟菌是一种不常见的急性细菌性结膜炎病原体。在这份简短的报告中,我们描述了一例免疫功能正常的成年男性脑膜炎球菌结膜炎病例,并回顾了相关文献。患者到眼科门诊就诊,主诉眼部严重不适、灼热和发红已超过两周,经裂隙灯检查,诊断为轻度结膜炎。对眼部拭子进行微生物培养后发现有菌落生长,经纯化培养,确定为 B 血清群脑膜炎双球菌。诊断为原发性脑膜炎双球菌结膜炎,除了局部使用莫西沙星眼药水外,还对患者肌肉注射头孢曲松,治疗 2 周后,患者的临床症状有所改善,最终完全康复,与微生物学检查结果一致。眼科医生必须意识到原发性脑膜炎球菌结膜炎病例的可能性,即使这种病例并不常见,也需要使用全身抗生素进行治疗,并对其密切接触者进行适当的抗生素化学预防。