Acute Myeloid Leukemia with NPM1 Mutation and Disseminated Leukemia Cutis: Achievement of Molecular Complete Remission by Venetoclax/Azacitidine Combination in a Very Old Patient.

IF 1.7 4区医学 Q3 HEMATOLOGY

Acta Haematologica Pub Date : 2023-01-01 Epub Date: 2023-05-17 DOI:10.1159/000531101

Pasquale Niscola, Carla Mazzone, Stefano Fratoni, Nicolina Rita Ardu, Laura Cesini, Marco Giovannini, Tiziana Ottone, Lucia Anemona, Maria Teresa Voso, Paolo de Fabritiis

引用次数: 1

Abstract

We describe a case of acute myeloid leukemia with NPM1 mutation and disseminated leukemia cutis in a very old patient, who achieved a long-lasting response to the azacitidine/venetoclax combination with molecular complete remission, given the potential value of this rarely observed clinical outcome.

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NPM1突变的急性髓细胞白血病和播散性白血病：Venetoclax/阿扎胞苷联合治疗高龄患者实现分子完全缓解。

我们描述了一例NPM1突变的急性髓系白血病和一名高龄患者的播散性白血病皮肤，考虑到这种罕见的临床结果的潜在价值，该患者对阿扎胞苷/venetoclax组合获得了持久的反应并获得了分子完全缓解。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Acta Haematologica 医学-血液学

CiteScore

4.90

自引率

0.00%

发文量

审稿时长

6-12 weeks

期刊介绍： ''Acta Haematologica'' is a well-established and internationally recognized clinically-oriented journal featuring balanced, wide-ranging coverage of current hematology research. A wealth of information on such problems as anemia, leukemia, lymphoma, multiple myeloma, hereditary disorders, blood coagulation, growth factors, hematopoiesis and differentiation is contained in first-rate basic and clinical papers some of which are accompanied by editorial comments by eminent experts. These are supplemented by short state-of-the-art communications, reviews and correspondence as well as occasional special issues devoted to ‘hot topics’ in hematology. These will keep the practicing hematologist well informed of the new developments in the field.