Clinico-cytomorphological Spectrum of Calcinosis Cutis.

IF 1 4区 医学 Q4 MEDICAL LABORATORY TECHNOLOGY
Journal of Cytology Pub Date : 2023-01-01 Epub Date: 2023-03-13 DOI:10.4103/joc.joc_75_22
Malvika Shastri, Pratibha Gautam, Preeti Diwaker, Priyanka Gogoi, Vinod K Arora
{"title":"Clinico-cytomorphological Spectrum of Calcinosis Cutis.","authors":"Malvika Shastri,&nbsp;Pratibha Gautam,&nbsp;Preeti Diwaker,&nbsp;Priyanka Gogoi,&nbsp;Vinod K Arora","doi":"10.4103/joc.joc_75_22","DOIUrl":null,"url":null,"abstract":"<p><strong>Introduction: </strong>The deposition of calcium in the skin is known as calcinosis cutis. It can affect any part of the body and can mimic soft tissue or bony lesions clinically.</p><p><strong>Aim: </strong>To describe the clinical and cytomorphologic features of calcinosis cutis on fine needle aspiration cytology smears.</p><p><strong>Materials and methods: </strong>A total of 17 cases reported as calcinosis cutis on fine needle aspiration cytology were reviewed for the available clinical and cytological details.</p><p><strong>Results: </strong>The cohort included both adult and pediatric patients. Clinically, the lesions appeared as painless swellings of variable sizes. The common sites affected were the scrotum, iliac region, scalp, pinna, neck, axilla, elbow, arm, thigh, and gluteal region. Aspirate was chalky white, paste-like in all the cases. The cytologic evaluation revealed amorphous crystalline deposits of calcium along with histiocytes, lymphocytes, and multinucleated giant cells.</p><p><strong>Conclusions: </strong>Calcinosis cutis has a wide spectrum of clinical presentations. Fine needle aspiration cytology is a minimally invasive approach for diagnosing calcinosis cutis, thus eliminating the need for more extensive biopsy procedures.</p>","PeriodicalId":50217,"journal":{"name":"Journal of Cytology","volume":null,"pages":null},"PeriodicalIF":1.0000,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10167833/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Cytology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.4103/joc.joc_75_22","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2023/3/13 0:00:00","PubModel":"Epub","JCR":"Q4","JCRName":"MEDICAL LABORATORY TECHNOLOGY","Score":null,"Total":0}
引用次数: 0

Abstract

Introduction: The deposition of calcium in the skin is known as calcinosis cutis. It can affect any part of the body and can mimic soft tissue or bony lesions clinically.

Aim: To describe the clinical and cytomorphologic features of calcinosis cutis on fine needle aspiration cytology smears.

Materials and methods: A total of 17 cases reported as calcinosis cutis on fine needle aspiration cytology were reviewed for the available clinical and cytological details.

Results: The cohort included both adult and pediatric patients. Clinically, the lesions appeared as painless swellings of variable sizes. The common sites affected were the scrotum, iliac region, scalp, pinna, neck, axilla, elbow, arm, thigh, and gluteal region. Aspirate was chalky white, paste-like in all the cases. The cytologic evaluation revealed amorphous crystalline deposits of calcium along with histiocytes, lymphocytes, and multinucleated giant cells.

Conclusions: Calcinosis cutis has a wide spectrum of clinical presentations. Fine needle aspiration cytology is a minimally invasive approach for diagnosing calcinosis cutis, thus eliminating the need for more extensive biopsy procedures.

Abstract Image

Abstract Image

Abstract Image

皮肤钙化症的临床细胞形态学谱。
引言:钙在皮肤中的沉积被称为钙化性皮肤病。它可以影响身体的任何部位,在临床上可以模拟软组织或骨损伤。目的:在细针吸取细胞学涂片上描述钙化性皮肤的临床和细胞形态学特征。材料和方法:对细针吸取细胞学检查中报告的17例皮肤钙化症进行回顾性分析,以了解可用的临床和细胞学细节。结果:该队列包括成人和儿童患者。临床上,病变表现为大小不等的无痛性肿胀。受影响的常见部位是阴囊、髂区、头皮、耳廓、颈部、腋窝、肘部、手臂、大腿和臀大区。吸气器呈粉白色,在所有情况下都像浆糊一样。细胞学评估显示,钙与组织细胞、淋巴细胞和多核巨细胞一起存在无定形结晶沉积。结论:钙化性皮肤病具有广泛的临床表现。细针抽吸细胞学检查是诊断钙化性皮肤病的一种微创方法,因此无需进行更广泛的活检程序。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
Journal of Cytology
Journal of Cytology MEDICAL LABORATORY TECHNOLOGY-
CiteScore
1.80
自引率
7.70%
发文量
34
审稿时长
46 weeks
期刊介绍: The Journal of Cytology is the official Quarterly publication of the Indian Academy of Cytologists. It is in the 25th year of publication in the year 2008. The journal covers all aspects of diagnostic cytology, including fine needle aspiration cytology, gynecological and non-gynecological cytology. Articles on ancillary techniques, like cytochemistry, immunocytochemistry, electron microscopy, molecular cytopathology, as applied to cytological material are also welcome. The journal gives preference to clinically oriented studies over experimental and animal studies. The Journal would publish peer-reviewed original research papers, case reports, systematic reviews, meta-analysis, and debates.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信